Niazi Muhammad Raphay, Iqbal Qasim Zafar, Mishiyev Danil, Narula Naureen, Abdul Sattar Saud Bin, Zia Zeeshan, Haider Muhammad Adnan, Chalhoub Michel
Staten Island University Hospital, Northwell, USA.
Medical Student at Allama Iqbal Medical College, Lahore, Pakistan.
Respir Med Case Rep. 2020 Nov 13;31:101262. doi: 10.1016/j.rmcr.2020.101262. eCollection 2020.
Epstein Barr Virus (EBV) is one of the herpes viruses that is responsible for causing infectious mononucleosis, lymphomas, and carcinomas primarily in immunocompromised individuals. We present a case of EBV-induced pneumonitis in an immunocompetent female, successfully treated with steroids. The patient is a 70 year-old female with a history of infectious mononucleosis in her teens who presented to the emergency room with worsening shortness of breath, associated with cough and fever. She underwent extensive work up and her serologic workup revealed positive anti-EBV antibodies, pointing towards the diagnosis of EBV induced pneumonitis. EBV-induced Pneumonitis is a very rare entity and is especially hardly seen among immunocompetent individuals. This interesting case shows that in this new era of viral pneumonias, EBV induced pneumonitis should be considered among differentials when dealing with lung infections. Prompt initiation of treatment with steroids or antiviral medication may result in complete recovery. The choices among treatment options can be individualized according to the severity of disease, course of disease progression, and side effect profile of medications. In our case we were able to successfully treat the patient with high dose steroids only.
爱泼斯坦-巴尔病毒（EBV）是一种疱疹病毒，主要在免疫功能低下的个体中引发传染性单核细胞增多症、淋巴瘤和癌症。我们报告一例免疫功能正常的女性发生EBV诱发的肺炎，经类固醇治疗成功。该患者为70岁女性，青少年时期有传染性单核细胞增多症病史，因气促加重、伴有咳嗽和发热就诊于急诊室。她接受了全面检查，血清学检查显示抗EBV抗体呈阳性，提示诊断为EBV诱发的肺炎。EBV诱发的肺炎是一种非常罕见的疾病，在免疫功能正常的个体中尤其罕见。这个有趣的病例表明，在这个病毒性肺炎的新时代，在处理肺部感染时，鉴别诊断应考虑EBV诱发的肺炎。及时开始使用类固醇或抗病毒药物治疗可能会完全康复。治疗方案的选择可根据疾病的严重程度、疾病进展过程以及药物的副作用情况进行个体化。在我们的病例中，仅用高剂量类固醇就成功治疗了患者。
