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弥漫性星形细胞瘤与一种不寻常表型的诊断困境:一例报告。

Diffuse astrocytoma and the diagnostic dilemma of an unusual phenotype: A case report.

作者信息

Alshoabi Sultan A, Alareqi Amal A, Omer Awatef M, Suliman Awadia G, Daqqaq Tareef S

机构信息

Department of Diagnostic Radiology Technology, College of Applied Medical Sciences, Taibah University, Almadinah Almunawwarah, 42312, Kingdom of Saudi Arabia.

Department of Radiology, University of Science and Technology Hospital (USTH), Sana'a, Republic of Yemen.

出版信息

Radiol Case Rep. 2020 Dec 3;16(2):319-326. doi: 10.1016/j.radcr.2020.11.023. eCollection 2021 Feb.

DOI:10.1016/j.radcr.2020.11.023
PMID:33304444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7718471/
Abstract

Diffuse astrocytoma is an infiltrating type of glioma (World Health Organization grade II), which even with histopathology, is difficult to diagnose. Magnetic resonance imaging (MRI) is the cornerstone for diagnoses and follow-up of brain gliomas. This report describes a case of diffuse astrocytoma in a 48-year-old man who presented with sudden right-sided weakness and repeated convulsive attacks. On brain computed tomography, the case was diagnosed and treated as an acute infarction. Ten days later, the patient returned with a total loss of consciousness. Brain MRI images revealed an irregularly outlined lesion involving the splenium of the corpus callosum that extended into the left periventricular parietal lobe of the brain with cystic foci in the septum pellucidum. Contrast-enhanced and new sequences of MRI was helpful in approach to diagnosis because of its superior tissue characterization. The histopathology results ultimately confirmed the diagnosis of diffuse astrocytoma. The patient died postoperatively.

摘要

弥漫性星形细胞瘤是一种浸润性胶质瘤(世界卫生组织二级),即使通过组织病理学检查也难以诊断。磁共振成像(MRI)是脑胶质瘤诊断和随访的基石。本报告描述了一例48岁男性弥漫性星形细胞瘤病例,该患者表现为突发右侧肢体无力和反复惊厥发作。在脑部计算机断层扫描中,该病例被诊断并当作急性梗死进行治疗。十天后,患者再次就诊时已完全失去意识。脑部MRI图像显示胼胝体压部有一个轮廓不规则的病变,延伸至左侧脑室旁顶叶,透明隔内有囊性病灶。MRI的增强扫描和新序列因其出色的组织特征有助于诊断。组织病理学结果最终确诊为弥漫性星形细胞瘤。患者术后死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/501bfe7d994f/gr7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/501bfe7d994f/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/d8ce2a8f5270/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/5e1f3f0929fe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/aadfccdaec5e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/12e80ea1cff4/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/e47c52ceb36c/gr5.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506c/7718471/501bfe7d994f/gr7.jpg

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