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一匹患有垂体中间部肿瘤的母马的葡萄糖代谢

Glucose metabolism in a pony mare with a tumour of the pituitary gland pars intermedia.

作者信息

Auer D E, Wilson R G, Groenendyk S, Filippich L J

机构信息

Department of Veterinary Pathology and Public Health, University of Queensland, St. Lucia.

出版信息

Aust Vet J. 1987 Dec;64(12):379-82. doi: 10.1111/j.1751-0813.1987.tb09609.x.

DOI:10.1111/j.1751-0813.1987.tb09609.x
PMID:3330656
Abstract

A case of pituitary dependent hyperadrenocorticism in a horse is reported. Clinical signs included hirsutism, polydipsia and general debility. The horse was persistently hyperglycaemic and glucose values were unchanged following subcutaneous administration of insulin. Resting cortisol values were normal, but dexamethasone suppression of cortisol concentration was shorter than normal. Plasma glucose, cortisol, insulin and glucagon concentrations were measured as part of an intravenous glucose tolerance test. The patient responses were different from those in a control pony.

摘要

报道了一例马垂体依赖性肾上腺皮质功能亢进病例。临床症状包括多毛症、多饮和全身虚弱。该马持续高血糖,皮下注射胰岛素后血糖值无变化。静息皮质醇值正常,但地塞米松对皮质醇浓度的抑制作用比正常情况短。作为静脉葡萄糖耐量试验的一部分,测量了血浆葡萄糖、皮质醇、胰岛素和胰高血糖素浓度。患者的反应与对照小马不同。

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