Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Greece.
Department of Obstetrics and Gynaecology, University Hospitals of Birmingham, UK.
J Gynecol Obstet Hum Reprod. 2021 Mar;50(3):102036. doi: 10.1016/j.jogoh.2020.102036. Epub 2020 Dec 8.
Current scientific evidence reveals the importance of the human microbiome in health and disease. The presence of microbiota within the male and female reproductive tract has been well-documented and present theories imply that a possible disruption of their concentrations may have adverse effects on reproductive health and reproductive outcomes. Altered endometrial and vaginal microbiome could potential affect the reproductive outcome in infertile couples undergoing assisted reproductive techniques. Analysis of seminal fluids could also facilitate a prompt and appropriate approach in cases of abnormal male reproductive microflora. Essential knowledge on this subject could provide fertility experts better understanding with regards to unexplained fertility, increasing the success rates of ARTs. In this review, we summarise the current knowledge on the microbiota of the male and female reproductive tract and its impact on the success rates of ARTs in infertile couples.
目前的科学证据揭示了人类微生物组在健康和疾病中的重要性。男性和女性生殖道内存在微生物群已得到充分证实，现有理论表明，其浓度可能发生的破坏可能对生殖健康和生殖结果产生不利影响。子宫内膜和阴道微生物组的改变可能会对接受辅助生殖技术的不孕夫妇的生殖结果产生潜在影响。精液分析也可以为异常男性生殖菌群的情况提供及时和适当的处理方法。关于这个主题的基本知识可以使生育专家更好地理解不明原因的生育能力，提高辅助生殖技术的成功率。在这篇综述中，我们总结了男性和女性生殖道微生物组及其对不孕夫妇辅助生殖技术成功率的影响的现有知识。
