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警惕克罗恩病:眼眶肌炎作为胃肠道表现之前的首发症状

Keep an Eye Out for Crohn's Disease: Orbital Myositis as the Initial Sign before Gastrointestinal Manifestations.

作者信息

Hoilat Gilles Jadd, Subedi Abinash, Ayas Mohamad Fekredeen, Ozden Nuri

机构信息

SUNY Upstate Medical University, Department of Medicine, Syracuse, NY, USA.

Ascension St. John Hospital, Department of Medicine, Detroit, MI, USA.

出版信息

Eur J Case Rep Intern Med. 2020 Oct 1;7(12):001964. doi: 10.12890/2020_001964. eCollection 2020.

DOI:10.12890/2020_001964
PMID:33313010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7727631/
Abstract

UNLABELLED

Extraintestinal manifestations of Crohn's disease sometimes occur and can present prior to intestinal symptoms. Ocular manifestations of Crohn's disease are considered rare, with orbital myositis an even rarer manifestation with only a handful of cases reported in the literature. We present the case of a young woman who was diagnosed with orbital myositis, which was initially attributed to pseudotumor cerebri after an extensive negative work-up. Months later, the patient presented with haematochezia, and was subsequently diagnosed with Crohn's disease.

LEARNING POINTS

Orbital myositis is a rare manifestation of inflammatory bowel disease (IBD), and even more rarely is the initial presentation before the development of intestinal luminal disease.Orbital myositis is a rare extraintestinal manifestation of Crohn's disease and mimics thyroid ophthalmopathy. When a thyroid function test is negative, it is important to keep IBD in mind.

摘要

未标注

克罗恩病的肠外表现有时会出现,且可能在肠道症状之前出现。克罗恩病的眼部表现被认为较为罕见,眼眶肌炎则更为罕见,文献中仅报道了少数病例。我们报告了一名年轻女性的病例,她被诊断为眼眶肌炎,在经过广泛的阴性检查后,最初被归因于假性脑瘤。数月后,患者出现便血,随后被诊断为克罗恩病。

学习要点

眼眶肌炎是炎症性肠病(IBD)的罕见表现,在肠道腔内疾病发展之前作为初始表现更为罕见。眼眶肌炎是克罗恩病罕见的肠外表现,可模仿甲状腺眼病。当甲状腺功能检查为阴性时,记住炎症性肠病很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/5776461c5c33/1964_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/23049d8a8b29/1964_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/03d2a7f3593f/1964_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/5776461c5c33/1964_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/23049d8a8b29/1964_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/03d2a7f3593f/1964_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d508/7727631/5776461c5c33/1964_Fig3.jpg

相似文献

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Eur J Case Rep Intern Med. 2020 Oct 1;7(12):001964. doi: 10.12890/2020_001964. eCollection 2020.
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本文引用的文献

1
Myositis as an Initial Presentation of Ulcerative Colitis before Gastrointestinal Symptoms.以肌炎作为溃疡性结肠炎的首发表现,先于胃肠道症状出现。
Pediatr Gastroenterol Hepatol Nutr. 2020 May;23(3):297-303. doi: 10.5223/pghn.2020.23.3.297. Epub 2020 May 8.
2
The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease.首部关于炎症性肠病肠外表现的欧洲循证共识
J Crohns Colitis. 2016 Mar;10(3):239-54. doi: 10.1093/ecco-jcc/jjv213. Epub 2015 Nov 27.
3
Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature.
阿达木单抗治疗克罗恩病停用英夫利昔单抗后发生眼眶肌炎 1 例报告并文献复习
BMC Gastroenterol. 2013 Apr 4;13:59. doi: 10.1186/1471-230X-13-59.
4
The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study.炎症性肠病肠外疾病的患病率:一项基于人群的研究。
Am J Gastroenterol. 2001 Apr;96(4):1116-22. doi: 10.1111/j.1572-0241.2001.03756.x.