Key Lab of Natural Product Chemistry and Application at Universities of Education Department of Xinjiang Uygur Autonomous Region, Yili Normal University, Yining, China.
School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, China.
Nat Prod Res. 2022 Jul;36(13):3353-3359. doi: 10.1080/14786419.2020.1858410. Epub 2020 Dec 17.
Two new naphthalene derivatives, named naphthalene A () and naphthalene B (), together with eight known compounds () were isolated from dichloromethane fraction of The structures of compounds were elucidated on the basis of spectroscopic analysis and absolute configurations were established based on electronic circular dichroism data. Compounds and exhibited moderate activity, increasing Glucose transporter 4 (GLUT-4) translocation by 1.62 and 1.87 folds, respectively.
从二氯甲烷部分分离得到两种新的萘衍生物，命名为萘 A（）和萘 B（），以及八种已知化合物（）。基于光谱分析阐明了化合物的结构，并根据电子圆二色性数据确定了绝对构型。化合物和表现出中等活性，分别使葡萄糖转运蛋白 4（GLUT-4）易位增加 1.62 和 1.87 倍。
