Yang L L, Zhang Q, Zhang Y Q, Sun J H, Zhao M, Xi B
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University/Children Cardiovascular Research Center of Shandong University, Ji'nan 250012, China.
Department of Food Nutrition and Child Health Care, Zibo Center for Disease Control and Prevention, Zibo 255026, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Dec 6;54(12):1461-1464. doi: 10.3760/cma.j.cn112150-20200610-00857.
Cardiovascular disease (CVD) has been an important public health issue in China. Recently, the prevalence of obesity, elevated blood pressure, hyperglycemia, dyslipidemia, and unhealthy lifestyles was high in Chinese children and adolescents, which might increase the risk of short-term target organ damage and adult CVD. Therefore, we selected one primary school in Huantai County, Zibo City between November 2017 and January 2018 to establish the Huantai Childhood Cardiovascular Health Cohort Study. The aim of this project was to investigate the effects of childhood exposures on short-term target organ damage and adult CVD, and to provide evidence to curb the epidemic of CVD in China from the source. A total of 1 515 children aged 6-11 years old were included at the baseline. In this paper, we will introduce the overall design of the survey, including participants, methods, quality control, basic characteristics of the participants, study limitations, and future directions, which might provide some useful implications for similar researches in the future.
心血管疾病（CVD）一直是中国一个重要的公共卫生问题。最近，中国儿童和青少年中肥胖、高血压、高血糖、血脂异常以及不健康生活方式的患病率很高，这可能会增加短期靶器官损害和成人CVD的风险。因此，我们于2017年11月至2018年1月在淄博市桓台县选择了一所小学，开展桓台儿童心血管健康队列研究。该项目的目的是调查儿童暴露因素对短期靶器官损害和成人CVD的影响，并从源头上为遏制中国CVD的流行提供证据。基线时共纳入了1515名6至11岁的儿童。在本文中，我们将介绍该调查的总体设计，包括参与者、方法、质量控制、参与者的基本特征、研究局限性以及未来方向，这可能会为未来类似研究提供一些有益的启示。
