• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

分子印迹聚合物用于食品样品中污染物检测的最新进展与未来趋势

Recent Advances and Future Trends in the Detection of Contaminants by Molecularly Imprinted Polymers in Food Samples.

作者信息

Gao Mingkun, Gao Yuhang, Chen Ge, Huang Xiaodong, Xu Xiaomin, Lv Jun, Wang Jing, Xu Donghui, Liu Guangyang

机构信息

Key Laboratory of Vegetables Quality and Safety Control, Laboratory of Quality & Safety Risk Assessment for Vegetable Products, Ministry of Agriculture and Rural Affairs of China, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.

Key Laboratory of Agro-Product Quality and Safety, Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Ministry of Agriculture Beijing, Beijing, China.

出版信息

Front Chem. 2020 Dec 1;8:616326. doi: 10.3389/fchem.2020.616326. eCollection 2020.

DOI:10.3389/fchem.2020.616326
PMID:33335893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7736048/
Abstract

Drug residues, organic dyes, heavy metals, and other chemical pollutants not only cause environmental pollution, but also have a serious impact on food safety. Timely and systematic summary of the latest scientific advances is of great importance for the development of new detection technologies. In particular, molecularly imprinted polymers (MIPs) can mimic antibodies, enzymes and other biological molecules to recognize, enrich, and separate contaminants, with specific recognition, selective adsorption, high affinity, and strong resistance characteristics. Therefore, MIPs have been widely used in chemical analysis, sensing, and material adsorption. In this review, we first describe the basic principles and production processes of molecularly imprinted polymers. Secondly, an overview of recent applications of molecularly imprinted polymers in sample pre-treatment, sensors, chromatographic separation, and mimetic enzymes is highlighted. Finally, a brief assessment of current technical issues and future trends in molecularly imprinted polymers is also presented.

摘要

药物残留、有机染料、重金属及其他化学污染物不仅会造成环境污染，还会对食品安全产生严重影响。及时且系统地总结最新科学进展对于新型检测技术的发展至关重要。特别是，分子印迹聚合物（MIPs）能够模拟抗体、酶及其他生物分子来识别、富集和分离污染物，具有特异性识别、选择性吸附、高亲和力和强抗性等特点。因此，MIPs已广泛应用于化学分析、传感及材料吸附领域。在本综述中，我们首先描述了分子印迹聚合物的基本原理和制备过程。其次，重点概述了分子印迹聚合物在样品预处理、传感器、色谱分离及模拟酶方面的近期应用。最后，还对分子印迹聚合物当前的技术问题和未来趋势进行了简要评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/cb7d3b4294c0/fchem-08-616326-g0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/4737493408bb/fchem-08-616326-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/9756a1d72dd3/fchem-08-616326-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/6baf5e34364c/fchem-08-616326-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/2fc5003952ab/fchem-08-616326-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/4ab5d904e996/fchem-08-616326-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/04c41adbadcb/fchem-08-616326-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/676c5fcfbbe2/fchem-08-616326-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/146791275b31/fchem-08-616326-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/cfea8d52050b/fchem-08-616326-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/5f57f275e243/fchem-08-616326-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/48499fcc3597/fchem-08-616326-g0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/1a49f13d9ea3/fchem-08-616326-g0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/cb7d3b4294c0/fchem-08-616326-g0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/4737493408bb/fchem-08-616326-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/9756a1d72dd3/fchem-08-616326-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/6baf5e34364c/fchem-08-616326-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/2fc5003952ab/fchem-08-616326-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/4ab5d904e996/fchem-08-616326-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/04c41adbadcb/fchem-08-616326-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/676c5fcfbbe2/fchem-08-616326-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/146791275b31/fchem-08-616326-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/cfea8d52050b/fchem-08-616326-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/5f57f275e243/fchem-08-616326-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/48499fcc3597/fchem-08-616326-g0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/1a49f13d9ea3/fchem-08-616326-g0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c7/7736048/cb7d3b4294c0/fchem-08-616326-g0013.jpg

相似文献

1
Recent Advances and Future Trends in the Detection of Contaminants by Molecularly Imprinted Polymers in Food Samples.分子印迹聚合物用于食品样品中污染物检测的最新进展与未来趋势
Front Chem. 2020 Dec 1;8:616326. doi: 10.3389/fchem.2020.616326. eCollection 2020.
2
Recent progress of the research of metal-organic frameworks-molecularly imprinted polymers (MOFs-MIPs) in food safety detection field.金属有机骨架-分子印迹聚合物（MOFs-MIPs）在食品安全检测领域的研究进展。
Food Chem. 2024 Nov 15;458:140330. doi: 10.1016/j.foodchem.2024.140330. Epub 2024 Jul 3.
3
Molecularly Imprinted Polymer as an Antibody Substitution in Pseudo-immunoassays for Chemical Contaminants in Food and Environmental Samples.分子印迹聚合物在食品和环境样品中化学污染物的拟免疫分析中的抗体替代作用。
J Agric Food Chem. 2018 Mar 21;66(11):2561-2571. doi: 10.1021/acs.jafc.7b05577. Epub 2018 Feb 28.
4
A critical review of molecularly imprinted polymers for the analysis of organic pollutants in environmental water samples.分子印迹聚合物在环境水样中有机污染物分析中的应用的综述评价。
J Chromatogr A. 2020 Mar 15;1614:460603. doi: 10.1016/j.chroma.2019.460603. Epub 2019 Oct 7.
5
Advances in fabrication of molecularly imprinted electrochemical sensors for detection of contaminants and toxicants.用于检测污染物和毒物的分子印迹电化学传感器的制作方法的进展。
Environ Res. 2022 Sep;212(Pt C):113359. doi: 10.1016/j.envres.2022.113359. Epub 2022 May 5.
6
Newest applications of molecularly imprinted polymers for extraction of contaminants from environmental and food matrices: A review.最新应用的分子印迹聚合物从环境和食品基质中提取污染物：综述。
Anal Chim Acta. 2017 Jun 29;974:1-26. doi: 10.1016/j.aca.2017.04.042. Epub 2017 May 5.
7
Molecularly imprinted polymer-based electrochemical sensors for environmental analysis.用于环境分析的分子印迹聚合物基电化学传感器。
Biosens Bioelectron. 2021 Jan 15;172:112719. doi: 10.1016/j.bios.2020.112719. Epub 2020 Oct 20.
8
Recent Advances and Perspectives of Molecularly Imprinted Polymer-Based Fluorescent Sensors in Food and Environment Analysis.基于分子印迹聚合物的荧光传感器在食品与环境分析中的研究进展与展望
Nanomaterials (Basel). 2019 Jul 18;9(7):1030. doi: 10.3390/nano9071030.
9
Recent advances and future prospects in molecularly imprinted polymers-based electrochemical biosensors.基于分子印迹聚合物的电化学生物传感器的最新进展和未来展望。
Biosens Bioelectron. 2018 Feb 15;100:56-70. doi: 10.1016/j.bios.2017.08.058. Epub 2017 Aug 30.
10
Molecularly imprinted polymers for sensing gaseous volatile organic compounds: opportunities and challenges.用于检测气态挥发性有机化合物的分子印迹聚合物：机遇与挑战。
Environ Pollut. 2022 Oct 15;311:119931. doi: 10.1016/j.envpol.2022.119931. Epub 2022 Aug 14.

引用本文的文献

1
Molecularly Imprinted Polymer Sensor Empowered by Bound States in the Continuum for Selective Trace-Detection of TGF-beta.基于连续体中的束缚态的分子印迹聚合物传感器用于 TGF-β的选择性痕量检测。
Adv Sci (Weinh). 2024 Nov;11(41):e2401843. doi: 10.1002/advs.202401843. Epub 2024 Sep 5.
2
Development of a dual-template molecularly imprinted electrochemical sensor for the simultaneous detection of depression markers 5-HT and Glu.开发一种双模板分子印迹电化学传感器，用于同时检测抑郁标志物 5-HT 和 Glu。
Mikrochim Acta. 2024 Aug 9;191(9):528. doi: 10.1007/s00604-024-06558-z.
3
Magnetic nanoparticles fabricated/integrated with microfluidics for biological applications: A review.

本文引用的文献

1
Nano-sized FeO@SiO-molecular imprinted polymer as a sorbent for dispersive solid-phase microextraction of melatonin in the methanolic extract of Portulaca oleracea, biological, and water samples.纳米级FeO@SiO分子印迹聚合物作为一种吸附剂，用于马齿苋甲醇提取物、生物样品和水样中褪黑素的分散固相微萃取。
Talanta. 2021 Jan 1;221:121620. doi: 10.1016/j.talanta.2020.121620. Epub 2020 Sep 5.
2
Combining capillary electromigration with molecular imprinting techniques towards an optimal separation and determination.将毛细管电迁移与分子印迹技术相结合以实现最佳分离和测定。
Talanta. 2021 Jan 1;221:121546. doi: 10.1016/j.talanta.2020.121546. Epub 2020 Sep 1.
3
磁性纳米粒子与微流控技术的生物应用：综述。
Biomed Microdevices. 2024 Jan 25;26(1):13. doi: 10.1007/s10544-023-00693-9.
4
An Overview on Recent Advances in Biomimetic Sensors for the Detection of Perfluoroalkyl Substances.用于检测全氟烷基物质的仿生传感器的最新进展概述。
Sensors (Basel). 2023 Dec 26;24(1):130. doi: 10.3390/s24010130.
5
Application of Chitosan-Based Molecularly Imprinted Polymer in Development of Electrochemical Sensor for -Aminophenol Determination.壳聚糖基分子印迹聚合物在用于测定对氨基苯酚的电化学传感器开发中的应用。
Polymers (Basel). 2023 Apr 7;15(8):1818. doi: 10.3390/polym15081818.
6
Preparation and Application of Molecularly Imprinted Polymers for Flavonoids: Review and Perspective.分子印迹聚合物在黄酮类化合物中的制备及应用：综述与展望。
Molecules. 2022 Oct 29;27(21):7355. doi: 10.3390/molecules27217355.
7
Current Scenario of Pathogen Detection Techniques in Agro-Food Sector.农业食品领域病原体检测技术的现状。
Biosensors (Basel). 2022 Jul 4;12(7):489. doi: 10.3390/bios12070489.
8
Advances in Detection of Antibiotic Pollutants in Aqueous Media Using Molecular Imprinting Technique-A Review.利用分子印迹技术检测水介质中抗生素污染物的研究进展——综述
Biosensors (Basel). 2022 Jun 23;12(7):441. doi: 10.3390/bios12070441.
9
Adsorption and selectivity studies of direct and magnetite-cored molecularly imprinted polymers (MIPs and magMIPs) towards chosen chalcones investigated with various analytical methods.采用多种分析方法对直接法和以磁铁矿为核的分子印迹聚合物（MIPs和magMIPs）对选定查耳酮的吸附和选择性进行了研究。
RSC Adv. 2021 Jul 21;11(41):25334-25347. doi: 10.1039/d1ra03391c. eCollection 2021 Jul 19.
10
Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin.用于选择性吸附4-羟基香豆素的磁性表面分子印迹聚合物
Front Chem. 2022 Apr 7;10:862777. doi: 10.3389/fchem.2022.862777. eCollection 2022.
Molecularly imprinted polymers immobilized on graphene oxide film for monolithic fiber solid phase microextraction and ultrasensitive determination of triphenyl phosphate.
基于氧化石墨烯膜的分子印迹聚合物整体纤维固相微萃取及其对磷酸三苯酯的高灵敏检测
Anal Chim Acta. 2020 Oct 9;1133:1-10. doi: 10.1016/j.aca.2020.08.003. Epub 2020 Aug 11.
4
SPR nanosensor based on molecularly imprinted polymer film with gold nanoparticles for sensitive detection of aflatoxin B1.基于分子印迹聚合物薄膜和金纳米粒子的 SPR 纳米传感器，用于灵敏检测黄曲霉毒素 B1。
Talanta. 2020 Nov 1;219:121219. doi: 10.1016/j.talanta.2020.121219. Epub 2020 Jun 10.
5
A functional ratio fluorescence sensor platform based on the graphene/Mn-ZnS quantum dots loaded with molecularly imprinted polymer for selective and visual detection sinapic acid.一种基于负载分子印迹聚合物的石墨烯/锰锌硫量子点的功能比率荧光传感器平台，用于选择性和可视化检测芥子酸。
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jan 5;244:118845. doi: 10.1016/j.saa.2020.118845. Epub 2020 Aug 16.
6
Nanomaterials-based solid phase extraction and solid phase microextraction for heavy metals food toxicity.基于纳米材料的重金属食品毒性固相萃取和固相微萃取
Food Chem Toxicol. 2020 Nov;145:111704. doi: 10.1016/j.fct.2020.111704. Epub 2020 Aug 25.
7
Selective solid-phase extraction of organophosphorus pesticides and their oxon-derivatives from water samples using molecularly imprinted polymer followed by high-performance liquid chromatography with UV detection.采用分子印迹聚合物固相萃取技术对水样中的有机磷农药及其氧代衍生物进行选择性萃取，然后采用高效液相色谱-紫外检测法进行检测。
J Chromatogr A. 2020 Aug 30;1626:461346. doi: 10.1016/j.chroma.2020.461346. Epub 2020 Jun 14.
8
A surfactant-mediated sol-gel method for the preparation of molecularly imprinted polymers and its application in a biomimetic immunoassay for the detection of protein.表面活性剂介导的溶胶-凝胶法制备分子印迹聚合物及其在仿生免疫测定检测蛋白质中的应用。
J Pharm Biomed Anal. 2020 Oct 25;190:113511. doi: 10.1016/j.jpba.2020.113511. Epub 2020 Jul 31.
9
In-line molecularly imprinted polymer solid phase extraction-capillary electrophoresis coupled with tandem mass spectrometry for the determination of patulin in apple-based food.在线分子印迹聚合物固相萃取-毛细管电泳串联质谱法测定苹果食品中的棒曲霉素。
Food Chem. 2021 Jan 1;334:127607. doi: 10.1016/j.foodchem.2020.127607. Epub 2020 Jul 19.
10
Functional polymers in photoelectrochemical biosensing.光电化学生物传感中的功能聚合物。
Bioelectrochemistry. 2020 Dec;136:107590. doi: 10.1016/j.bioelechem.2020.107590. Epub 2020 Jul 2.