Department of Infection Disease, People's Hospital of Deyang, Deyang, China.
Eur Rev Med Pharmacol Sci. 2020 Dec;24(23):12522-12526. doi: 10.26355/eurrev_202012_24049.
The present study aimed to explore the transmission pattern and the incubation period of coronavirus disease 2019 (COVID-19) as well as the clinical characteristics of infants with COVID-19 to provide a scientific basis for introducing further measures to reduce the infection rate and control the pandemic.
A descriptive epidemiological study of 18 patients with COVID-19 in People's Hospital of Deyuan was carried out. Among these patients, 16 cases were connected with clusters (11 family-cluster cases and 5 public-cluster cases). The basic characteristics, clinical symptoms, and epidemiological characteristics of the patients were considered in the investigation.
The median age of the 18 patients was 44.5 years (37.5-52.0 years), and there were 10 males and 8 females in the sample. The main clinical symptoms were fever and cough. The epidemiological characteristics were as follows: (1) the median incubation period was 8 days (with an interquartile range of 4-12 days); (2) the incubation period in one case was ≥18 days; (3) one infant patient was asymptomatic prior to their diagnosis; and (4) two asymptomatic patients had a positive nucleic acid test after their family members were diagnosed with COVID-19.
COVID-19 can be transmitted in many ways, including via respiratory droplets and indirect contact, and it spreads easily among close contacts. People with a history of contact with areas affected by the disease should be isolated at home for 14 days. Moreover, attention should be focused on the issues of asymptomatic infectors, asymptomatic infants, and infants with mild symptoms.
本研究旨在探讨 2019 年冠状病毒病（COVID-19）的传播模式和潜伏期，以及 COVID-19 婴儿的临床特征，为进一步采取措施降低感染率和控制疫情提供科学依据。
对德源人民医院 18 例 COVID-19 患者进行描述性流行病学研究。其中 16 例与聚集性病例有关（11 例家庭聚集性病例和 5 例公共聚集性病例）。在调查中考虑了患者的基本特征、临床症状和流行病学特征。
18 例患者的中位年龄为 44.5 岁（37.5-52.0 岁），样本中男性 10 例，女性 8 例。主要临床症状为发热和咳嗽。流行病学特征如下：（1）中位潜伏期为 8 天（四分位距 4-12 天）；（2）1 例潜伏期≥18 天；（3）1 例婴儿患者在诊断前无症状；（4）2 例无症状患者在其家庭成员被诊断为 COVID-19 后核酸检测呈阳性。
COVID-19 可通过呼吸道飞沫和间接接触等多种途径传播，且在密切接触者中传播容易。与疫区有接触史的人员应在家隔离 14 天。此外，应关注无症状感染者、无症状婴儿和症状轻微的婴儿等问题。
