Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
School of Medicine and Hepatitis Research Center, College of Medicine, and Center for Cancer Research and Center for Liquid Biopsy and Cohort Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2021 Jan;37(1):7-11. doi: 10.1002/kjm2.12345. Epub 2020 Dec 18.
The Nobel Prize for Physiology or Medicine, in the year 2020, has been awarded to three scientists, Harvey Alter, Michael Houghton, and Charles Rice, for jointly discovering the hepatitis C virus (HCV). This remarkable achievement is a huge breakthrough in the fight against hepatitis C. Most importantly, their pioneering works have successfully saved millions of lives by acting as the foundation for sensitive blood tests and effective antivirals. Inspired by the 2020 Nobel Prize winners, this review article honors their great efforts and discusses several unmet needs in the path toward HCV elimination. In Taiwan, we adopted a micro-elimination approach plus patient-centric outreach program to tackle the obstacles that stand in the way of HCV elimination. With its significant results, HCV elimination could be achieved in the near future.
2020 年诺贝尔生理学或医学奖授予哈维·J·阿尔特(Harvey J. Alter)、迈克尔·霍顿(Michael Houghton)和查尔斯·M·赖斯(Charles M. Rice)三位科学家,以表彰他们共同发现丙型肝炎病毒(HCV)。这一杰出成就,是抗击丙型肝炎的巨大突破。最重要的是,他们的开创性工作,通过灵敏血液检测和有效抗病毒药物的研发,成功拯救了数百万人的生命。本文以 2020 年诺贝尔生理学或医学奖得主为榜样,对他们的杰出工作表示敬意,并讨论丙型肝炎消除道路上的一些尚未满足的需求。在台湾,我们采用微消除方法和以患者为中心的外展计划,解决消除丙型肝炎的障碍。有了显著的成果,在不久的将来丙型肝炎可能被消除。