Walter Reed National Military Medical Center.
Program of Reproductive Endocrinology and Infertility, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Clin Obstet Gynecol. 2021 Mar 1;64(1):65-75. doi: 10.1097/GRF.0000000000000595.
Polycystic ovary syndrome (PCOS) is a common endocrinopathy that has been associated with impaired fertility. This chapter reviews the underlying pathophysiology of PCOS and the associated fertility barriers of the condition. Psychologic concerns, hypothalamic-pituitary, ovarian, and mitochondria dysfunction, obesity, and the role of vitamin D in PCOS are considered with respect to fertility. Lastly, pregnancy risk factors associated with PCOS are also reviewed.
多囊卵巢综合征（PCOS）是一种常见的内分泌疾病，与生育能力受损有关。本章回顾了 PCOS 的潜在病理生理学以及该病症的相关生育障碍。从生育角度考虑了心理问题、下丘脑-垂体、卵巢和线粒体功能障碍、肥胖以及维生素 D 在 PCOS 中的作用。最后，还回顾了与 PCOS 相关的妊娠风险因素。
