Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Guangdong Provincial Engineering Technology Research Center of Environmental and Health risk Assessment, Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne VIC 3004, Australia.
J Hazard Mater. 2021 Apr 5;407:124750. doi: 10.1016/j.jhazmat.2020.124750. Epub 2020 Dec 2.
Evidence concerning exposure to air pollution and visual impairment is scarce. We evaluated the associations of ambient air pollution with visual impairment and visual acuity levels in Chinese schoolchildren. We recruited 61,995 children from 7 provinces/municipalities across China. Concentrations of air pollutants (i.e., particulate matter with an aerodynamic diameter of ≤ 1.0 µm [PM], ≤ 2.5 µm [PM], and 10 µm [PM] as well as nitrogen dioxides [NO]) were measured using machine learning methods. Visual acuity levels were measured using standard protocols. We used SAS PROC SURVEYLOGISTIC to assess the association between air pollution and visual impairment. An interquartile range increase in PM, PM, PM, and NO was associated with a 1.133- (95% CI, 1.035-1.240), 1.267- (95% CI, 1.082-1.484), 1.142- (95% CI, 1.019-1.281), and 1.276-fold (95% CI, 1.173-1.388) increased odds of visual impairment, and the associations were stronger in children being boys, older, living in rural areas, and born to parents who had a lower educational level or smoked, compared to their counterparts. These results suggest that exposure to air pollution were positively associated with the odds of visual impairment, and the association may be modified by children's age, sex, and residential area as well as parental education level and cigarette smoking.
有关空气污染与视力障碍的证据很少。我们评估了环境空气污染与中国学童视力障碍和视力水平之间的关联。我们从中国 7 个省/直辖市招募了 61995 名儿童。使用机器学习方法测量了空气污染物（即空气动力学直径≤1.0μm[PM]、≤2.5μm[PM]和 10μm[PM]以及二氧化氮[NO]）的浓度。使用标准协议测量了视力水平。我们使用 SAS PROC SURVEYLOGISTIC 来评估空气污染与视力障碍之间的关联。PM、PM、PM 和 NO 的四分位距增加与视力障碍的几率增加 1.133（95%CI，1.035-1.240）、1.267（95%CI，1.082-1.484）、1.142（95%CI，1.019-1.281）和 1.276 倍（95%CI，1.173-1.388）有关，而在男孩、年龄较大、居住在农村地区以及父母教育程度较低或吸烟的儿童中，这些关联更强。这些结果表明，暴露于空气污染与视力障碍的几率呈正相关，并且这种关联可能会受到儿童的年龄、性别和居住地区以及父母的教育水平和吸烟习惯的影响。
