Xu Y, Ling S G, Dong Z, Ke X, Lu L N, Zou H D
Shanghai Eye Diseases Prevention &Treatment Center/Shanghai Eye Hospital, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200040, China.
Zhonghua Yan Ke Za Zhi. 2020 Dec 11;56(12):920-927. doi: 10.3760/cma.j.cn112142-20200409-00257.
To develop a fundus image quality assessment system based on computer vision technology and to verify its accuracy by comparing the results of artificial discrimination and using this system. The process of image evaluation was divided into four modules: fundus image preprocessing, fundus image quality evaluation, fundus image content detection and evaluation result output. The system was designed to automatically evaluate the image quality of each fundus image, identify the optic disc and macula, and judge whether the image was qualified or not according to the image quality discrimination rules. A total of 2 397 fundus images of 787 type 2 diabetes patients were selected as the test data set. The average age of the patients, including 384 males and 403 females, was (69.65±19.09) years old. The images were taken by the staff of community health service centers in Shanghai with a fundus camera. The fundus image quality assessment system was used to conduct quality control and classification of the data set. At the same time, 12 professional fundus picture readers were employed to conduct manual quality control and classification of this data set. The system quality control results and artificial quality discrimination results were compared and analyzed. The fundus image quality assessment system automatically recognized left and right eyes and eye positions on the input fundus images. The quality control interface included four indicator lights, which respectively corresponded to the images with the optic disc or macula as the center of the left or right eye. Evaluation of each fundus image was completed within 1 second, and the results were automatically displayed on the user interface. The 2 397 fundus photos were identified manually as 1 846 qualified photos and 551 unqualified photos. Among the unqualified images, 62 (11.27%) were too dark, 51 (9.27%) were too bright, 59 (10.73%) were not clear in the macular area, 36 (6.54%) showed no macula or optic disc, 125 (22.73%) could not present the fundus structure, 175 (31.82%) were blurred, and 42 (7.64%) were blocked. The results of the system and manual assessment were consistent in 1 788 qualified images (96.86%) and 550 unqualified images (99.82%), with an overall consistency rate of 97.54%. The fundus image quality assessment system can achieve highly consistent results with the professional judgment of ophthalmologists and has the characteristics of objectivity. .
基于计算机视觉技术开发一种眼底图像质量评估系统,并通过比较人工判别结果与使用该系统的结果来验证其准确性。图像评估过程分为四个模块:眼底图像预处理、眼底图像质量评估、眼底图像内容检测和评估结果输出。该系统旨在自动评估每张眼底图像的质量,识别视盘和黄斑,并根据图像质量判别规则判断图像是否合格。选取787例2型糖尿病患者的2397张眼底图像作为测试数据集。患者平均年龄(69.65±19.09)岁,其中男性384例,女性403例。图像由上海社区卫生服务中心工作人员使用眼底相机拍摄。使用眼底图像质量评估系统对数据集进行质量控制和分类。同时,聘请12名专业眼底图像阅片人员对该数据集进行人工质量控制和分类。对系统质量控制结果和人工质量判别结果进行比较分析。眼底图像质量评估系统能自动识别输入眼底图像上的左右眼及眼位。质量控制界面包括四个指示灯,分别对应以视盘或黄斑为中心的左眼或右眼的图像。每张眼底图像的评估在1秒内完成,结果自动显示在用户界面上。2397张眼底照片经人工判别为1846张合格照片和551张不合格照片。在不合格图像中,62张(11.27%)太暗,51张(9.27%)太亮,59张(10.73%)黄斑区不清晰,36张(6.54%)未显示黄斑或视盘,125张(22.73%)无法呈现眼底结构,175张(31.82%)模糊,42张(7.64%)有遮挡。系统评估结果与人工评估结果在1788张合格图像(96.86%)和550张不合格图像(99.82%)中一致,总体一致率为97.54%。眼底图像质量评估系统与眼科医生的专业判断结果高度一致,具有客观性。