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屎肠球菌SF 68在小鼠实验性感染中的作用

[Role of Enterococcus faecium SF 68 in experimental infection in mice].

作者信息

Chisari G, lo Bue A M, Drago L, Abbiati R, Castiglioni G, Gismondo M R

出版信息

G Ital Chemioter. 1989 Jan-Dec;36(1-3):65-8.

PMID:2488915
Abstract

The normal intestinal flora is an important defence against various infectious agents. It also allows important metabolic stages in the host. The Authors studied the ability of Enterococcus faecium SF 68 to protect the mice (Swiss strain) from infection by Salmonella typhi and its role when used with penicillin in infection by Staphylococcus aureus. Our results showed that SF 68, determined a good protection against infection. Moreover the association E. faecium SF 68-antibiotic lowers the mortality rate in the infected mice compared with the control group.

摘要

正常肠道菌群是抵御各种感染因子的重要防线。它还参与宿主体内重要的代谢过程。作者研究了屎肠球菌SF 68保护小鼠(瑞士品系)免受伤寒沙门氏菌感染的能力,以及其与青霉素联合使用时在金黄色葡萄球菌感染中的作用。我们的结果表明,SF 68对感染具有良好的保护作用。此外,与对照组相比,屎肠球菌SF 68与抗生素联合使用可降低感染小鼠的死亡率。

相似文献

1
[Role of Enterococcus faecium SF 68 in experimental infection in mice].屎肠球菌SF 68在小鼠实验性感染中的作用
G Ital Chemioter. 1989 Jan-Dec;36(1-3):65-8.
2
[Protection of an oral vaccine against experimental infection of mice and its role combined with the administration of penicillin].[一种口服疫苗对小鼠实验性感染的保护作用及其与青霉素联合给药的作用]
G Batteriol Virol Immunol. 1990 Jan-Dec;83(1-12):84-7.
3
[Protection against experimental infections in mice by an oral vaccine and its combined role when administered with antibiotics].[口服疫苗对小鼠实验性感染的保护作用及其与抗生素联合使用时的协同作用]
G Batteriol Virol Immunol. 1987 Jan-Dec;80(1-12):177-81.
4
Intestinal bacterial flora and host defense mechanisms.肠道菌群与宿主防御机制。
Tokai J Exp Clin Med. 1986;11 Suppl:65-79.
5
[Interference of the intestinal ecosystem of mice in the oral administration of lyophilized live bacteria].[口服冻干活菌对小鼠肠道生态系统的干扰]
G Batteriol Virol Immunol. 1986 Jan-Jun;79(1-6):113-23.
6
[The intestinal ecosystem of mice after administration of a polyvalent oral vaccine].[给予多价口服疫苗后小鼠的肠道生态系统]
G Batteriol Virol Immunol. 1987 Jan-Dec;80(1-12):15-24.
7
Ecological mechanism of protection of intestinal bacterial flora against Salmonella typhimurium infection.肠道菌群抵御鼠伤寒沙门氏菌感染的生态保护机制。
Tokai J Exp Clin Med. 1990 May;15(2-3):111-21.
8
[Comparative study on antibacterial effects of huangqin-tang and its metabolites produced by intestinal flora].
Zhongguo Zhong Yao Za Zhi. 2003 Mar;28(3):243-6.
9
[Intestinal flora of inpatients and isolation frequency of methicillin-resistant Staphylococcus aureus].
Rinsho Byori. 1993 Jun;41(6):661-5.
10
Use of cefazolin microspheres to treat localized methicillin-resistant Staphylococcus aureus infections in rats.使用头孢唑林微球治疗大鼠局部耐甲氧西林金黄色葡萄球菌感染。
J Surg Res. 1999 Sep;86(1):97-102. doi: 10.1006/jsre.1999.5686.

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