Schartner Michael M, Timmermann Christopher
Département des Neurosciences Fondamentales, Université de Genève Rue Michel Servet 1 CH-1211 Geneva Switzerland.
Department of Medicine, Centre for Psychedelic Research, Division of Brain Sciences, Imperial College London, UK The Commonwealth Building, The Hammersmith Hospital, Du Cane Road, London W12 0NN.
Neurosci Conscious. 2020 Dec 12;2020(1):niaa024. doi: 10.1093/nc/niaa024. eCollection 2020.
The regulatory role of the serotonergic system on conscious perception can be investigated perturbatorily with psychedelic drugs such as N,N-Dimethyltryptamine. There is increasing evidence that the serotonergic system gates prior (endogenous) and sensory (exogenous) information in the construction of a conscious experience. Using two generative deep neural networks as examples, we discuss how such models have the potential to be, firstly, an important medium to illustrate phenomenological visual effects of psychedelics-besides paintings, verbal reports and psychometric testing-and, secondly, their utility to conceptualize biological mechanisms of gating the influence of exogenous and endogenous information on visual perception.
5-羟色胺能系统对意识感知的调节作用可以通过诸如N，N-二甲基色胺等致幻药物进行干扰性研究。越来越多的证据表明，5-羟色胺能系统在构建有意识体验的过程中，对先前（内源性）和感官（外源性）信息起到了闸门作用。以两个生成式深度神经网络为例，我们讨论了此类模型如何有潜力成为，首先，除绘画、言语报告和心理测量测试之外，用以阐释致幻剂现象学视觉效应的重要媒介，其次，其在概念化对外源性和内源性信息对视觉感知影响进行闸门控制的生物学机制方面的效用。
