Cheong Kang Hao, Wen Tao, Lai Joel Weijia
Science, Mathematics and Technology Cluster Singapore University of Technology and Design 8 Somapah Rd, S487372 Singapore.
Adv Sci (Weinh). 2020 Nov 5;7(24):2002324. doi: 10.1002/advs.202002324. eCollection 2020 Dec.
COVID-19, also known as SARS-CoV-2, is a coronavirus that is highly pathogenic and virulent. It spreads very quickly through close contact, and so in response to growing numbers of cases, many countries have imposed lockdown measures to slow its spread around the globe. The purpose of a lockdown is to reduce reproduction, that is, the number of people each confirmed case infects. Lockdown measures have worked to varying extents but they come with a massive price. Nearly every individual, community, business, and economy has been affected. In this paper, switching strategies that take into account the total "cost" borne by a community in response to COVID-19 are proposed. The proposed cost function takes into account the health and well-being of the population, as well as the economic impact due to the lockdown. The model allows for a comparative study to investigate the effectiveness of various COVID-19 suppression strategies. It reveals that both the strategy to implement a lockdown and the strategy to maintain an open community are individually losing in terms of the total "cost" per day. However, switching between these two strategies in a certain manner can paradoxically lead to a winning outcome-a phenomenon attributed to Parrondo's paradox.
新冠病毒病(COVID-19),也称为严重急性呼吸综合征冠状病毒2(SARS-CoV-2),是一种具有高致病性和高传染性的冠状病毒。它通过密切接触传播得非常快,因此,随着病例数量的不断增加,许多国家都实施了封锁措施,以减缓其在全球的传播。封锁的目的是降低病毒繁殖数,即每个确诊病例感染的人数。封锁措施在不同程度上发挥了作用,但付出了巨大代价。几乎每个个人、社区、企业和经济体都受到了影响。本文提出了一些切换策略,这些策略考虑了社区应对新冠病毒病所承担的总“成本”。所提出的成本函数考虑了人口的健康和福祉,以及封锁造成的经济影响。该模型允许进行比较研究,以调查各种新冠病毒病抑制策略的有效性。研究表明,无论是实施封锁的策略还是维持社区开放的策略,就每天的总“成本”而言,各自都有损失。然而,以某种方式在这两种策略之间切换却可能产生有利结果——这一现象被归因于巴龙多悖论。