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大网膜成形术治疗放射性臂丛神经病变

Treatment of radiation-induced brachial plexopathy with omentoplasty.

作者信息

de Oliveira Adilson José Manuel, Castro João Paulo de Souza, Foroni Luciano Henrique, Siqueira Mário Gilberto, Martins Roberto Sérgio

机构信息

Universidade de São Paulo (USP), Faculdade de Medicina, Hospital das Clínicas, Instituto de Psiquiatria, Peripheral Nerves Group, São Paulo, SP, Brasil.

Clínica Girassol, Neurosurgery Department, Luanda, Angola.

出版信息

Autops Case Rep. 2020 Sep 2;10(3):e2020202. doi: 10.4322/acr.2020.202.

DOI:10.4322/acr.2020.202
PMID:33344306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7703345/
Abstract

Radiation-induced brachial plexus neuropathy (RIBPN) is a rare and delayed non-traumatic injury to the brachial plexus, which occurs following radiation therapy to the chest wall, neck, and/or axilla in previously treated patients with cancer. The incidence of RIBPN is more common in patients treated for carcinoma of the breast and Hodgkin lymphoma. With the improvement in radiation techniques, the incidence of injury to the brachial plexus following radiotherapy has dramatically reduced. The currently reported incidence is 1.2% in women irradiated for breast cancer. The progression of symptoms is gradual in about two-thirds of cases; the patients may initially present with paresthesia followed by pain, and later progress to motor weakness in the affected limb. We present the case of a 68-year-old female patient with breast cancer submitted to surgery, chemotherapy, and radiotherapy in the year 2000. Eighteen years later, she developed symptoms and signs compatible with RIBPN and was successfully submitted to omentoplasty for pain control. Omentoplasty is an alternative treatment for RIBPN refractory to conservative treatment, which seems to be effective in improving neuropathic pain. However, postoperative worsening of the motor strength is a real possibility, and all candidates for this type of surgery must be informed about the risk of this complication.

摘要

放射性臂丛神经病变(RIBPN)是一种罕见的、迟发性的臂丛神经非创伤性损伤,发生于既往接受过癌症治疗的患者在接受胸壁、颈部和/或腋窝放疗之后。RIBPN在乳腺癌和霍奇金淋巴瘤患者中更为常见。随着放疗技术的改进,放疗后臂丛神经损伤的发生率已显著降低。目前报道的乳腺癌放疗女性患者的发生率为1.2%。约三分之二的病例症状呈渐进性发展;患者最初可能出现感觉异常,随后出现疼痛,后期进展为受累肢体的运动无力。我们报告一例68岁女性乳腺癌患者,2000年接受了手术、化疗和放疗。18年后,她出现了与RIBPN相符的症状和体征,并成功接受了网膜成形术以控制疼痛。网膜成形术是一种治疗保守治疗无效的RIBPN的替代方法,似乎对改善神经性疼痛有效。然而,术后运动力量确实有可能恶化,所有这类手术的候选患者都必须被告知这种并发症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901a/7703345/5abf33404d18/autopsy-10-3-e2020202-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901a/7703345/5abf33404d18/autopsy-10-3-e2020202-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901a/7703345/5abf33404d18/autopsy-10-3-e2020202-gf01.jpg

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本文引用的文献

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2
Clinical, Electrophysiological Findings in Adult Patients with Non-traumatic Plexopathies.非创伤性臂丛神经病成年患者的临床及电生理表现
Ann Rehabil Med. 2011 Dec;35(6):807-15. doi: 10.5535/arm.2011.35.6.807. Epub 2011 Dec 30.
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Radiation-induced Peripheral Neuropathy.放射性周围神经病变
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Radiation-induced brachial plexus neuropathy - aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment.放射性臂丛神经病变——病因发病机制、危险因素、鉴别诊断、症状与治疗
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Radiation-induced brachial plexopathy in women treated for carcinoma of the breast.接受乳腺癌治疗的女性发生放射性臂丛神经病变。
Clin Rehabil. 2002 Mar;16(2):160-5. doi: 10.1191/0269215502cr470oa.
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Timescale of evolution of late radiation injury after postoperative radiotherapy of breast cancer patients.乳腺癌患者术后放疗后晚期放射性损伤的演变时间尺度。
Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):745-50. doi: 10.1016/s0360-3016(00)00674-x.
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Radiation-induced brachial plexopathy: MR and clinical findings.放射性臂丛神经病变:磁共振成像及临床 findings。 (这里“findings”直译为“发现”,结合语境在医学领域可灵活处理为“表现”等更合适的表述,但题目要求不添加解释,所以保留原词)
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