Specific Modified mRNA Translation System.
作者信息
Magadum Ajit, Kurian Ann Anu, Chepurko Elena, Sassi Yassine, Hajjar Roger J, Zangi Lior
机构信息
Cardiovascular Research Center (A.M., A.A.K., E.C., Y.S., L.Z.), Icahn School of Medicine at Mount Sinai, New York.
Department of Genetics and Genomic Sciences (A.M., A.A.K., E.C., L.Z.), Icahn School of Medicine at Mount Sinai, New York.
出版信息
Circulation. 2020 Dec 22;142(25):2485-2488. doi: 10.1161/CIRCULATIONAHA.120.047211. Epub 2020 Dec 21.
Abstract
摘要
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本文引用的文献
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Optimizing Cardiac Delivery of Modified mRNA.优化修饰mRNA的心脏递送
Mol Ther. 2017 Jun 7;25(6):1306-1315. doi: 10.1016/j.ymthe.2017.03.016. Epub 2017 Apr 4.
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miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation.微小RNA-199a通过激活雷帕霉素靶蛋白（mTOR）损害自噬并诱导心肌肥大。
Cell Death Differ. 2017 Jul;24(7):1205-1213. doi: 10.1038/cdd.2015.95. Epub 2015 Jul 10.
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MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.微小RNA-208a是小鼠心脏肥大和传导的调节因子。
J Clin Invest. 2009 Sep;119(9):2772-86. doi: 10.1172/JCI36154. Epub 2009 Aug 10.
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The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes.肌肉特异性微小RNA miR-1和miR-133通过靶向心肌细胞中的HSP60、HSP70和半胱天冬酶-9对细胞凋亡产生相反的作用。
J Cell Sci. 2007 Sep 1;120(Pt 17):3045-52. doi: 10.1242/jcs.010728.
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