生物植入物表面：纤连蛋白的结合与成纤维细胞黏附

Bioimplant surfaces: binding of fibronectin and fibroblast adhesion.

作者信息

Cannas M, Denicolai F, Webb L X, Gristina A G

机构信息

Department of Human Anatomy, University of Turin, Italy.

出版信息

J Orthop Res. 1988;6(1):58-62. doi: 10.1002/jor.1100060108.

DOI:10.1002/jor.1100060108

PMID:3334739

Abstract

The adhesion of baby hamster kidney 21C/13 fibroblasts to surfaces of passivated titanium, carbon fibers, bioactive glasses B5 and B6, fibronectin-precoated passivated titanium, and fibronectin-precoated B6 was quantified. The order of adhesive cell avidity for the uncoated surfaces was passivated titanium (greatest), B6 and carbon fibers (intermediate), and B5 (least). Precoating with fibronectin enhanced the adhesive characteristics of fibroblasts on passivated titanium and B6 by 74% and 118%, respectively.

摘要

对幼仓鼠肾21C/13成纤维细胞在钝化钛、碳纤维、生物活性玻璃B5和B6、纤连蛋白预涂钝化钛以及纤连蛋白预涂B6表面的黏附情况进行了定量分析。未涂层表面的黏附细胞亲和力顺序为：钝化钛（最高）、B6和碳纤维（中等）、B5（最低）。用纤连蛋白预涂分别使成纤维细胞在钝化钛和B6上的黏附特性提高了74%和118%。