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生物植入物表面:纤连蛋白的结合与成纤维细胞黏附

Bioimplant surfaces: binding of fibronectin and fibroblast adhesion.

作者信息

Cannas M, Denicolai F, Webb L X, Gristina A G

机构信息

Department of Human Anatomy, University of Turin, Italy.

出版信息

J Orthop Res. 1988;6(1):58-62. doi: 10.1002/jor.1100060108.

DOI:10.1002/jor.1100060108
PMID:3334739
Abstract

The adhesion of baby hamster kidney 21C/13 fibroblasts to surfaces of passivated titanium, carbon fibers, bioactive glasses B5 and B6, fibronectin-precoated passivated titanium, and fibronectin-precoated B6 was quantified. The order of adhesive cell avidity for the uncoated surfaces was passivated titanium (greatest), B6 and carbon fibers (intermediate), and B5 (least). Precoating with fibronectin enhanced the adhesive characteristics of fibroblasts on passivated titanium and B6 by 74% and 118%, respectively.

摘要

对幼仓鼠肾21C/13成纤维细胞在钝化钛、碳纤维、生物活性玻璃B5和B6、纤连蛋白预涂钝化钛以及纤连蛋白预涂B6表面的黏附情况进行了定量分析。未涂层表面的黏附细胞亲和力顺序为:钝化钛(最高)、B6和碳纤维(中等)、B5(最低)。用纤连蛋白预涂分别使成纤维细胞在钝化钛和B6上的黏附特性提高了74%和118%。

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1
Bioimplant surfaces: binding of fibronectin and fibroblast adhesion.生物植入物表面:纤连蛋白的结合与成纤维细胞黏附
J Orthop Res. 1988;6(1):58-62. doi: 10.1002/jor.1100060108.
2
[In vitro biocompatibility: increase in the capacity for adhesion in fibroblasts by materials pretreated with fibronectin].[体外生物相容性:经纤连蛋白预处理的材料使成纤维细胞的黏附能力增强]
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Shear-aggregated fibronectin with anti-adhesive properties.具有抗黏附特性的剪切聚集纤维连接蛋白。
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[The fibronectin binding test: proposal of an experimental model for the evaluation of the biocompatibility of materials of orthopedic interest].[纤连蛋白结合试验:一种用于评估骨科相关材料生物相容性的实验模型的提议]
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Medicina (Kaunas). 2025 Jul 30;61(8):1384. doi: 10.3390/medicina61081384.
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Modulation of Cell Response through the Covalent Binding of Fibronectin to Titanium Substrates.通过纤连蛋白与钛基底的共价结合调节细胞反应。
J Funct Biomater. 2023 Jun 28;14(7):342. doi: 10.3390/jfb14070342.
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Biological functionalization of dental implants with fibronectin: a scanning electron microscopic study.
用纤连蛋白对牙种植体进行生物功能化:一项扫描电子显微镜研究。
Int J Health Sci (Qassim). 2014 Jan;8(1):57-66. doi: 10.12816/0006072.
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The effect of fibronectin-coated implant on canine osseointegration.纤连蛋白包被种植体对犬骨整合的影响。
J Periodontal Implant Sci. 2011 Oct;41(5):242-7. doi: 10.5051/jpis.2011.41.5.242. Epub 2011 Oct 31.