Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Glaucoma Division, Stein Eye Institute, David Geffen School of California, California, CA, USA.
Eur J Ophthalmol. 2021 Nov;31(6):3074-3079. doi: 10.1177/1120672120977354. Epub 2020 Dec 21.
To assess the vision-related quality of life in adult patients with a history of primary congenital glaucoma.
In a cross-sectional hospital-based study eligible patients with a history of primary congenital glaucoma aged more than 18 were recruited in the study. Patients with secondary glaucoma and monocular patients were excluded. All patients underwent a complete ophthalmologic examination. The subjects were requested to answer a Persian approved version of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) questionnaire.
A total of 23 congenital glaucoma patients have enrolled in the study. The mean age was 29.22 (9.3 SD) and mean IOP was 13.82 (5.19 SD) and 15.69 (5.26 SD) in right and left eyes, respectively. The mean number of medications was 1.13 (1.25 SD) in the right and 1.30 (1.18 SD) in the left eyes. Among all scores of NEI-VFQ-25, the lowest score belonged to mental health 53.71 (29.72) and the highest score was color vision score 83.69 (20.79). We found a significant influence of visual field defect on many subscales including general health and general vision ( = 0.007, = +0.65) and ( = 0.002, = +0.71) respectively. The Mean Defect (MD) was associated with low social functioning and peripheral vision too ( = 0.035, = +0.53) and ( = 0.001, = +0.76) respectively. Age had a negative impact on the general vision subscale ( = 0.003, = -0.59).
Our study showed that visual field defect was strongly associated with many subscales scores in (NEI VFQ-25) questionnaire.
评估原发性先天性青光眼成年患者的视觉相关生活质量。
在一项横断面医院基础研究中,招募了年龄超过 18 岁且有原发性先天性青光眼病史的合格患者。排除继发性青光眼和单眼患者。所有患者均接受了全面的眼科检查。要求患者回答经波斯语验证的 25 项国家眼科研究所视觉功能问卷(NEI VFQ-25)。
共有 23 名先天性青光眼患者纳入研究。右眼和左眼的平均年龄分别为 29.22(9.3 标准差)和 13.82(5.19 标准差)和 15.69(5.26 标准差)。右眼和左眼的平均用药数分别为 1.13(1.25 标准差)和 1.30(1.18 标准差)。在 NEI-VFQ-25 的所有评分中,得分最低的是心理健康 53.71(29.72),得分最高的是色觉评分 83.69(20.79)。我们发现视野缺损对许多子量表有显著影响,包括一般健康和一般视力( = 0.007, = +0.65)和( = 0.002, = +0.71)。平均缺损(MD)也与社会功能低下和周边视力差有关( = 0.035, = +0.53)和( = 0.001, = +0.76)。年龄对一般视力子量表有负面影响( = 0.003, = -0.59)。
我们的研究表明,视野缺损与(NEI VFQ-25)问卷中的许多子量表评分密切相关。