Becker Erica C, Tafader Asiya, Bath Roopjeet K
Internal Medicine, University of Connecticut Health, Farmington, USA.
Gastroenterology and Hepatology, University of Connecticut Health, Farmington, USA.
Cureus. 2022 Jul 10;14(7):e26712. doi: 10.7759/cureus.26712. eCollection 2022 Jul.
Neutropenic enterocolitis (NE) is a medical emergency that occurs in neutropenic patients characterized by diffuse circumferential mural thickening predominantly involving the cecum. It is not easily differentiated from various other abdominal conditions (i.e., appendicitis, intussusception, ischemic colitis, small bowel obstruction, pseudomembranous colitis, and viral gastroenteritis), but clinicians should be aware of the diagnostic criteria in order to assist with prompt diagnosis. Although standard treatment has yet to be established, it is necessary to initiate early supportive care to reduce mortality risk. Here we present a case of NE with small bowel obstruction in a patient with acute myeloid leukemia (AML). Clinical findings and CT abdomen/pelvis were consistent with NE. Unfortunately, the patient succumbed to the illness.
中性粒细胞减少性小肠结肠炎（NE）是一种发生在中性粒细胞减少患者中的医疗急症，其特征为弥漫性环形肠壁增厚，主要累及盲肠。它不易与其他各种腹部疾病（如阑尾炎、肠套叠、缺血性结肠炎、小肠梗阻、伪膜性结肠炎和病毒性肠胃炎）相区分，但临床医生应了解诊断标准以协助及时诊断。尽管尚未确立标准治疗方法，但有必要尽早开始支持性治疗以降低死亡风险。在此，我们报告一例急性髓系白血病（AML）患者并发NE伴小肠梗阻的病例。临床发现及腹部/盆腔CT与NE相符。不幸的是，该患者因病死亡。
