Neuromuscular and Neurodevelopment Disorders Research Group (Neuro-e-Motion), Faculty of Psychology and Education, University of Deusto, Spain.
Nutr Rev. 2021 Jun 4;79(7):802-813. doi: 10.1093/nutrit/nuaa113.
In recent years, the ketogenic diet has gained special relevance as a possible therapeutic alternative to some neurological and chronic diseases.
The aim of this systematic review was to answer the following question: Does a ketogenic diet improve cognitive skills in patients with Alzheimer's disease, Parkinson's disease, refractory epilepsy, and type 1 glucose deficiency syndrome? To define the research question, the PICOS criteria were used, following the guidelines of the PRISMA method.
Medline/PubMed, Elsevier Science Direct, Dialnet, EBSCOhost, Mediagraphic, Sage Journals, ProQuest, and Wiley Online Library databases were used.
After applying inclusion and exclusion criteria in accordance with the PRISMA method, a total of 63 entries published between 2004 and 2019 were used.
The records extracted were analyzed from a qualitative approach, so no statistical analysis was carried out.
Although scientific literature on the subject is scarce and there has tended to be a lack of scientific rigor, the studies reviewed confirmed the effectiveness of this diet in improving the cognitive symptomatology of the aforementioned diseases.
近年来，生酮饮食作为某些神经和慢性疾病的一种可能的治疗替代方法，具有特殊的意义。
本系统评价旨在回答以下问题：生酮饮食是否能改善阿尔茨海默病、帕金森病、难治性癫痫和 1 型葡萄糖缺乏综合征患者的认知技能？为了定义研究问题，使用了 PICOS 标准，遵循 PRISMA 方法的指南。
使用了 Medline/PubMed、Elsevier Science Direct、Dialnet、EBSCOhost、Mediagraphic、Sage Journals、ProQuest 和 Wiley Online Library 数据库。
根据 PRISMA 方法，应用纳入和排除标准后，共使用了 2004 年至 2019 年期间发表的 63 篇文章。
从定性的角度分析了提取的记录，因此没有进行统计分析。
尽管关于该主题的科学文献稀缺，而且往往缺乏科学严谨性，但综述中的研究证实了这种饮食在改善上述疾病的认知症状方面的有效性。
