COVID-19 大流行期间护士的压力、抑郁、焦虑和睡眠障碍患病率：系统评价和荟萃分析。

BACKGROUND: The new coronavirus disease's (COVID-19) high risk of infection can increase the workload of healthcare workers, especially nurses, as they are most of the healthcare workforce. These problems can lead to psychological problems. Therefore, the aim of this systematic review and meta-analysis to ascertain the present impact of the COVID-19 outbreak on the prevalence of stress, anxiety, depression and sleep disturbance among nurses. METHODS: A systematic review and meta-analysis were conducted. The following databases were searched: PubMed, CHINAL, MEDLINE, EMBASE, PsycINFO, MedRxiv and Google Scholar, from January 2020 up to 26th October 2020. Prevalence rates were pooled with meta-analysis using a random-effects model. Heterogeneity was tested using I-squared (I) statistics. RESULTS: A total of 93 studies (n = 93,112), published between January 2020 and September 2020, met the inclusion criteria. The overall prevalence of stress was assessed in 40 studies which accounted for 43% (95% CI 37-49). The pooled prevalence of anxiety was 37% (95% CI 32-41) in 73 studies. Depression was assessed in 62 studies, with a pooled prevalence of 35% (95% CI 31-39). Finally, 18 studies assessed sleep disturbance and the pooled prevalence was 43% (95% CI 36-50). CONCLUSION: This meta-analysis found that approximately one third of nurses working during the COVID-19 epidemic were suffering from psychological symptoms. This highlights the importance of providing comprehensive support strategies to reduce the psychological impact of the COVID-19 outbreak among nurses under pandemic conditions. Further longitudinal study is needed to distinguish of psychological symptoms during and after the infectious disease outbreaks.

背景：新型冠状病毒病（COVID-19）具有很高的感染风险，这增加了医护人员，尤其是护士的工作量，因为他们是医疗保健工作者中的大部分群体。这些问题可能导致心理问题。因此，本系统评价和荟萃分析的目的是确定 COVID-19 爆发对护士压力、焦虑、抑郁和睡眠障碍患病率的当前影响。

方法：进行了系统评价和荟萃分析。检索了以下数据库：PubMed、CHINAL、MEDLINE、EMBASE、PsycINFO、MedRxiv 和 Google Scholar，检索时间从 2020 年 1 月至 2020 年 10 月 26 日。使用随机效应模型对荟萃分析进行汇总。使用 I 平方（I）统计量检验异质性。

结果：共有 93 项研究（n=93,112），发表于 2020 年 1 月至 2020 年 9 月，符合纳入标准。40 项研究评估了整体压力发生率，占 43%（95%CI 37-49）。73 项研究评估了焦虑的总体患病率为 37%（95%CI 32-41）。62 项研究评估了抑郁，总体患病率为 35%（95%CI 31-39）。最后，18 项研究评估了睡眠障碍，总体患病率为 43%（95%CI 36-50）。

结论：本荟萃分析发现，大约三分之一在 COVID-19 流行期间工作的护士患有心理症状。这强调了在大流行期间为护士提供全面支持策略以减轻 COVID-19 爆发对心理的影响的重要性。需要进一步的纵向研究来区分传染病爆发期间和之后的心理症状。