Northwestern University, Chicago, Illinois.
Nova Southeastern University, Fort Lauderdale, Florida.
Curr Probl Cardiol. 2021 Mar;46(3):100763. doi: 10.1016/j.cpcardiol.2020.100763. Epub 2020 Dec 11.
Incidence of cardiovascular complications has increased during the COVID-19 (Coronavirus disease 2019) pandemic, both population-wide and in patients diagnosed with the disease. This increase has presented complications in patient care, leading to increased hospitalizations, adverse outcomes, and medical costs. A condition of interest is takotsubo syndrome, which may be associated with the novel coronavirus. To understand this connection, a narrative review was performed by analyzing primary studies and case reports available. The findings showed increased incidence of takotsubo cardiomyopathy in both the general population and COVID-19 patients. Proposed mechanisms for the linkage include generalized increases in psychological distress, the cytokine storm, increased sympathetic responses in COVID-19 patients, and microvascular dysfunction. Moreover, natural disasters are noted as likely being associated with increases of takotsubo syndrome. As the pandemic continues, treating COVID-19 as a systemic condition is imperative, with the increase in takotsubo syndrome marking a significant impact of the novel coronavirus.
心血管并发症的发生率在 COVID-19（2019 年冠状病毒病）大流行期间有所增加，无论是在人群中还是在被诊断患有该病的患者中都是如此。这种增加给患者护理带来了并发症，导致住院人数增加、不良后果和医疗费用增加。一个值得关注的情况是应激性心肌病，它可能与新型冠状病毒有关。为了了解这种联系，通过分析现有的主要研究和病例报告，进行了叙述性综述。研究结果表明，应激性心肌病在普通人群和 COVID-19 患者中的发生率都有所增加。提出的关联机制包括心理困扰的普遍增加、细胞因子风暴、COVID-19 患者交感神经反应增加和微血管功能障碍。此外，自然灾害也可能与应激性心肌病的增加有关。随着大流行的继续，将 COVID-19 视为一种系统性疾病是必要的，应激性心肌病的增加标志着新型冠状病毒的重大影响。
