Department of Old Age Psychiatry, GGZ inGeest, Amsterdam, the Netherlands.
Department of Psychiatry, Amsterdam Public Health Research institute, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Int J Geriatr Psychiatry. 2021 Jun;36(6):892-900. doi: 10.1002/gps.5489. Epub 2021 Jan 23.
Older adults with bipolar disorder (OABD) are vulnerable for a COVID-19 infection via multiple pathways. It is essential for OABD to adhere to the COVID-19 measures, with potential consequences for the psychiatric symptoms. This situation offers the unique opportunity to investigate factors of vulnerability and resilience that are associated with psychiatric symptoms in OABD.
This study included 81 OABD patients aged over 50 years. Factors measured at baseline in patients that participated in 2017/2018 were compared with factors measured during the COVID-19 outbreak.
Participants experienced less psychiatric symptoms during COVID-19 than (67.9% euthymic) than at baseline (40.7% euthymic). There was no difference in loneliness between COVID-19 and baseline. Not having children, more feelings of loneliness, lower mastery, passive coping style and neuroticism were associated with more psychiatric symptoms during COVID-19 measures.
Participants experienced less psychiatric symptoms during COVID-19 measures when compared to baseline. Our results indicate promising targets for psychological interventions aimed at curing and preventing recurrence in OABD and improving quality of life in this growing vulnerable group.
通过多种途径，患有双相情感障碍的老年患者（OABD）易感染 COVID-19。OABD 必须遵守 COVID-19 措施，这可能会对精神症状产生潜在影响。这种情况为研究与 OABD 精神症状相关的脆弱性和复原力因素提供了独特的机会。
本研究纳入了 81 名年龄在 50 岁以上的 OABD 患者。对 2017/2018 年参与研究的患者进行基线测量，将患者的基线测量结果与 COVID-19 爆发期间的测量结果进行比较。
与基线时（40.7%的患者病情稳定）相比，参与者在 COVID-19 期间的精神症状（67.9%的患者病情稳定）有所减轻。COVID-19 期间和基线时的孤独感没有差异。无子女、更多的孤独感、较低的掌控感、被动应对方式和神经质与 COVID-19 期间更多的精神症状有关。
与基线相比，参与者在 COVID-19 措施期间的精神症状有所减轻。我们的结果表明，针对 OABD 患者的治疗和预防复发，以及改善这一不断增长的脆弱群体的生活质量，有希望成为心理干预的目标。
