Hebei University of Chinese Medicine.
The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang City, Hebei, China.
Medicine (Baltimore). 2020 Dec 18;99(51):e23737. doi: 10.1097/MD.0000000000023737.
Chinese medicine has a unique theory and the Chinese herbal medicine treatment is based on the integral concepts and syndrome differentiation of the Traditional Chinese Medicine system. Although antibiotics remain the mainstay of SIBO treatment, various alternative or adjunctive therapies are available, including prokinetic agents, dietary interventions, probiotics, and herbal combinations. There is accumulating evidence demonstrating the antimicrobial properties of a growing number of herbs including garlic, black cumin, cloves, cinnamon, thyme, all-spices, bay leaves, mustard, and rosemary. This has prompted an interest in herbal therapy for the treatment of SIBO. Currently, there is no systematic review focusing on efficacy of CHM in the treatment of SIBO with PCOS, so our meta-analysis aims to comprehensively explore it. Meanwhile we will provide high-quality evidence to help patients, clinicians as well as health policymakers select better treatment strategy of PCOS.
We will search the following sources without restrictions for date, language, or publication status: PubMed, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL) Cochrane Library, EMBASE and China National Knowledge Infrastructure. We will apply a combination of Medical Subject Heading (MeSH) and free-text terms incorporating database-specific controlled vocabularies and text words to implement search strategies. We will also search the ongoing trials registered in the World Health Organization's International Clinical Trials Registry Platform. Besides, the previous relevant reviews conducted on CHM for SIBO and reference lists of included studies will also be searched.
This study will provide a reliable basis for the treatment of SIBO with CHM.
The findings will be an available reference to evaluate the efficacy and safety of CHM in the treatment of SIBO.
INPLASY202080004.
中医有独特的理论，中草药治疗是基于中医系统的整体观念和辨证论治。虽然抗生素仍然是 SIBO 治疗的主要方法，但也有各种替代或辅助疗法，包括促动力药、饮食干预、益生菌和草药组合。越来越多的证据表明，包括大蒜、黑孜然、丁香、肉桂、百里香、五香粉、月桂叶、芥末和迷迭香在内的许多草药具有抗菌特性。这促使人们对草药疗法治疗 SIBO 产生了兴趣。目前，尚无系统评价专门关注中药治疗多囊卵巢综合征合并 SIBO 的疗效，因此我们的荟萃分析旨在全面探讨这一问题。同时，我们将提供高质量的证据，帮助患者、临床医生和卫生政策制定者选择更好的多囊卵巢综合征治疗策略。
我们将在以下来源中进行无限制搜索，包括日期、语言和出版状态：PubMed、Web of Science、Cochrane 中央对照试验注册库（CENTRAL）Cochrane 图书馆、EMBASE 和中国国家知识基础设施。我们将采用结合医学主题词（MeSH）和自由文本术语的方法，纳入数据库特定的受控词汇和文本词，以实施搜索策略。我们还将搜索世界卫生组织国际临床试验注册平台上正在进行的试验。此外，还将搜索以前关于 CHM 治疗 SIBO 的相关综述以及纳入研究的参考文献列表。
本研究将为 CHM 治疗 SIBO 提供可靠的依据。
研究结果将为评估 CHM 治疗 SIBO 的疗效和安全性提供参考。
INPLASY202080004。
