Faculty of Medicine "Carl Gustav Carus", Health Sciences/ Public Health, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine "Carl Gustav Carus", Health Sciences/ Public Health, Technische Universität Dresden, Dresden, Germany.
BMJ Open. 2020 Dec 28;10(12):e037669. doi: 10.1136/bmjopen-2020-037669.
The incidence and prevalence of chronic inflammatory bowel diseases in childhood and adolescence is increasing and varies internationally. The systematic literature review aims to describe international epidemiological trends of chronic inflammatory bowel diseases in the child and adolescence age. A period from 1970 to 2019 will be taken into account when searching for suitable studies as well as geographical differences in the development of incidences will be presented.
The literature databases PubMed and Embase will be searched for the period from 01 January 1970 to 31 December 2019 using linked keywords. A manual search in bibliographies of already published and relevant systematic reviews will complete the systematic literature search. The included studies will be combined in a qualitative and quantitative synthesis and statistically evaluated.
Ethical approval is not required for this study as it is a systematicreview. The results will be submitted to peer-reviewed journals and presented in national andinternational meetings. This research received no specific grant from any funding agency inthe public, commercial or not-for-profit sectors. This systematic review protocol was registeredwith the International Prospective Register of Systematic Reviews (PROSPERO-NR:CRD42020168644).
儿童和青少年慢性炎症性肠病的发病率和患病率正在增加，并在国际上有所不同。本系统文献综述旨在描述儿童和青少年慢性炎症性肠病的国际流行趋势。在寻找合适的研究时，将考虑到 1970 年至 2019 年这一时期，同时还将介绍发病率发展的地理差异。
将使用相关联的关键词在文献数据库 PubMed 和 Embase 中搜索 1970 年 1 月 1 日至 2019 年 12 月 31 日的文献。已发表和相关系统综述的参考文献的手动搜索将完成系统文献搜索。将对纳入的研究进行定性和定量综合，并进行统计学评估。
由于本研究是系统评价，因此不需要伦理批准。研究结果将提交给同行评议期刊，并在国内外会议上展示。本研究没有从任何公共、商业或非营利部门的资助机构获得特定的资助。本系统评价方案已在国际前瞻性系统评价登记处（PROSPERO-NR: CRD42020168644）注册。
