Haidere Mohammad Faisal, Ratan Zubair Ahmed, Nowroz Senjuti, Zaman Sojib Bin, Jung You-Jung, Hosseinzadeh Hassan, Cho Jae Youl
Department of Soil, Water and Environment, University of Dhaka, Dhaka 1000, Bangladesh.
School of Health & Society, University of Wollongong, NSW 2500, Australia.
Biomol Ther (Seoul). 2021 Jan 1;29(1):1-10. doi: 10.4062/biomolther.2020.178.
COVID-19 has caused extensive human casualties with significant economic impacts around the globe, and has imposed new challenges on health systems worldwide. Over the past decade, SARS, Ebola, and Zika also led to significant concerns among the scientific community. Interestingly, the SARS and Zika epidemics ended before vaccine development; however, the scholarly community and the pharmaceutical companies responded very quickly at that time. Similarly, when the genetic sequence of SARSCoV-2 was revealed, global vaccine companies and scientists have stepped forward to develop a vaccine, triggering a race toward vaccine development that the whole world is relying on. Similarly, an effective and safe vaccine could play a pivotal role in eradicating COVID-19. However, few important questions regarding SARS-CoV-2 vaccine development are explored in this review.
新冠病毒已在全球造成大量人员伤亡，并产生了重大经济影响，给世界各地的卫生系统带来了新挑战。在过去十年中，非典、埃博拉和寨卡病毒也引起了科学界的高度关注。有趣的是，非典和寨卡疫情在疫苗研发完成之前就结束了；然而，当时学术界和制药公司反应非常迅速。同样，当新冠病毒的基因序列公布后，全球疫苗公司和科学家纷纷挺身而出研发疫苗，引发了一场全世界都寄予厚望的疫苗研发竞赛。同样，一种有效且安全的疫苗在根除新冠病毒方面可能会发挥关键作用。然而，本综述中很少探讨关于新冠病毒疫苗研发的几个重要问题。
