Friede A, Harris J R, Kobayashi J M, Shaw F E, Shoemaker-Nawas P C, Kane M A
Division of Viral Diseases, Centers for Disease Control, Atlanta, GA 30333.
Am J Public Health. 1988 Jan;78(1):26-9. doi: 10.2105/ajph.78.1.26.
In 1985, 6,991 Asian children were adopted by Americans. To estimate the risk that such children may transmit hepatitis B virus to their adoptive families, we conducted a cumulative-incidence follow-up study in the State of Washington. We examined the association between having adopted a hepatitis B surface antigen (HBsAg)-seropositive Asian child and serologic evidence of past or present hepatitis B virus infection in adoptive family members. Seven (9 per cent) of 77 family members exposed to an HBsAg-seropositive child had evidence of past or present infection compared with four (2 per cent) of 232 nonexposed (relative risk = 5.3; 90% confidence limits [CL] = 2.0-13.9). The risk was higher for those with prolonged exposure and was entirely restricted to parents.
1985年，6991名亚洲儿童被美国人收养。为了评估这些儿童将乙肝病毒传播给其收养家庭的风险，我们在华盛顿州开展了一项累积发病率随访研究。我们研究了收养乙肝表面抗原（HBsAg）血清学阳性亚洲儿童与收养家庭成员过去或现在感染乙肝病毒的血清学证据之间的关联。接触HBsAg血清学阳性儿童的77名家庭成员中有7名（9%）有过去或现在感染的证据，而232名未接触者中有4名（2%）（相对风险=5.3；90%置信区间[CL]=2.0-13.9）。长期接触者的风险更高，且完全局限于父母。
