Vernon T M, Wright R A, Kohler P F, Merrill D A
JAMA. 1976 Jun 28;235(26):2829-31.
Investigation of an outbreak of hepatitis A among members of an adoption organization implicated recently arrived Vietnamese orphans as the source of infection. A serologic study disclosed a 27% prevalence of hepatitis B surface antigen among Vietnamese orphans and a 23.1% (6 of 26) prevalence of hepatitis B antibody among American children of adopting families. Five of the six antibody-positive American children were in families with HBsAg-positive orphans. Thus,healthy orphans from high hepatitis incidence areas may transmit hepatitis B, as well as hepatitis A, in the family unit.
对一家收养机构成员中甲型肝炎暴发的调查表明,近期抵达的越南孤儿是感染源。一项血清学研究显示,越南孤儿中乙型肝炎表面抗原的流行率为27%,收养家庭的美国儿童中乙型肝炎抗体的流行率为23.1%(26例中有6例)。6例抗体呈阳性的美国儿童中有5例来自收养了HBsAg呈阳性孤儿的家庭。因此,来自肝炎高发地区的健康孤儿可能在家庭环境中传播乙型肝炎和甲型肝炎。