Federal University of Acre, Rio Branco, Brazil.
University of Campinas, Campinas, Brazil.
Clin Infect Dis. 2021 Sep 7;73(5):e1219-e1221. doi: 10.1093/cid/ciaa1895.
We studied 2351 participants with coronavirus disease 2019; 1177 (50%) reported previous dengue infection. Those without previous dengue had a higher risk of death (hazard ratio: .44; 95% confidence interval: .22-.89; P = .023) in 60-day follow-up. These findings raise the possibility that dengue might induce immunological protection against severe acute respiratory syndrome coronavirus 2.
我们研究了 2351 名 2019 年冠状病毒病患者;其中 1177 人(50%)报告了以前的登革热感染。在 60 天的随访中,无既往登革热感染的患者死亡风险更高(风险比:0.44;95%置信区间:0.22-0.89;P = 0.023)。这些发现提示登革热可能诱导对严重急性呼吸综合征冠状病毒 2 的免疫保护。