Department of Infectious, Tropical Diseases and Microbiology, I.R.C.C.S. Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024, Negrar di Valpolicella, Italy.
Laboratory Department, I.R.C.C.S. Sacro Cuore Don Calabria Hospital, Via Sempreboni 5, 37024, Negrar di Valpolicella, Italy.
Ticks Tick Borne Dis. 2021 Mar;12(2):101628. doi: 10.1016/j.ttbdis.2020.101628. Epub 2020 Dec 13.
We investigated the epidemiology, clinical manifestations, laboratory data and antibiotic treatment of Lyme borreliosis in the province of Verona, Northern Italy, during the period 2015-2019. One hundred and 29 cases of Lyme borreliosis were diagnosed in a single hospital representing 27 % of all cases reported in the Veneto region in the same period. The mean annual incidence of Lyme borreliosis was 0.992/100,000 inhabitants. A peak incidence of 2/100,000 inhabitants was observed in 2018. Early localized Lyme borreliosis was the most common presentation (74 %), followed by early disseminated Lyme borreliosis (21 %). One possible early Lyme neuroborreliosis and two cranial neuropathies were diagnosed. IgM and/or IgG borrelia antibodies were positive in 90 % of the cases. This significant increase of Lyme borreliosis incidence in the province of Verona highlights the need to increase knowledge on its epidemiology and clinical manifestation among both the general population and clinicians to allow early diagnosis and treatment.
我们调查了意大利北部威尼托地区维罗纳省 2015-2019 年期间莱姆病的流行病学、临床表现、实验室数据和抗生素治疗情况。在一家医院诊断出 129 例莱姆病，占同期威尼托地区报告的所有病例的 27%。莱姆病的年平均发病率为 0.992/100000 居民。2018 年发病率峰值为 2/100000 居民。早期局部莱姆病是最常见的表现（74%），其次是早期播散性莱姆病（21%）。诊断出 1 例可能的早期莱姆神经伯氏疏螺旋体病和 2 例颅神经病变。90%的病例 IgM 和/或 IgG 伯氏疏螺旋体抗体阳性。维罗纳省莱姆病发病率的显著增加突出表明，需要提高普通人群和临床医生对其流行病学和临床表现的认识，以便早期诊断和治疗。
