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老年男性中低睾酮水平与健康行为的患病率

Prevalence of Low Testosterone According to Health Behavior in Older Adults Men.

作者信息

Ko Duk Han, Kim Seong Eon, Lee Ji Young

机构信息

Department of Sports Science Convergence, Dongguk University, Seoul 04620, Korea.

Department of Physical Education, Sejong University, Seoul 05006, Korea.

出版信息

Healthcare (Basel). 2020 Dec 24;9(1):15. doi: 10.3390/healthcare9010015.

Abstract

Testosterone is a representative sex hormone for men, and low testosterone causes erectile dysfunction and cardiovascular disease. The purpose of this study was to investigate the association between low testosterone (LTT) and health behaviors, such as alcohol, smoking, and exercise habits. We included 2980 men aged 65 to 80. Total serum testosterone and body composition were measured. A testosterone level less than 300 ng/dL was defined as low testosterone. A questionnaire on smoking, alcohol, and exercise was included. The odds ratio (OR) of LTT was calculated through logistic regression. Model 1 only used age as the adjustment variable, whereas Model 2 adjusted for age, waist circumference, and smoking. The prevalence of LTT was 626 (21.0%). The prevalence of LTT was significant in fat mass (Model 1: OR, 2.133) and muscle mass (Model 1: medium OR, 2.130 and low OR, 3.022; Model 2: medium OR, 1.638 and low OR, 1.740). The prevalence of LTT was also different based on smoking (Model 1: OR, 1.590; Model 2: OR, 1.629) and strength exercise (Model 1: OR, 0.849; Model 2: OR, 0.923). In conclusion, high frequency strength exercise and smoking cessation lower the prevalence of low testosterone, and obesity and low muscle mass increase the prevalence of low testosterone.

摘要

睾酮是男性具有代表性的性激素,睾酮水平低会导致勃起功能障碍和心血管疾病。本研究的目的是调查低睾酮(LTT)与健康行为之间的关联,如饮酒、吸烟和运动习惯。我们纳入了2980名年龄在65至80岁之间的男性。测量了血清总睾酮和身体成分。睾酮水平低于300 ng/dL被定义为低睾酮。纳入了一份关于吸烟、饮酒和运动的问卷。通过逻辑回归计算LTT的比值比(OR)。模型1仅将年龄作为调整变量,而模型2则对年龄、腰围和吸烟进行了调整。LTT的患病率为626例(21.0%)。LTT的患病率在脂肪量方面具有统计学意义(模型1:OR,2.133),在肌肉量方面也具有统计学意义(模型1:中等肌肉量OR,2.130,低肌肉量OR,3.022;模型2:中等肌肉量OR,1.638,低肌肉量OR,1.740)。LTT的患病率在吸烟方面也有所不同(模型1:OR,1.590;模型2:OR,1.629),在力量训练方面也有所不同(模型1:OR,0.849;模型2:OR,0.923)。总之,高频力量训练和戒烟可降低低睾酮的患病率,而肥胖和低肌肉量会增加低睾酮的患病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2d3/7824172/dc1fe62d2342/healthcare-09-00015-g001.jpg

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