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不断变化的生活方式:新兴成年期的城市化、饮食转变与内分泌健康

Lifestyle in flux: urbanization, dietary shifts, and endocrine health in emerging adulthood.

作者信息

Joshi Om Vijay, Savale Ronit Rohidas, Nalage Dinesh, Biradar Ashwini, Sontakke Tejswini

机构信息

Department of Biotechnology, Institute of Biosciences and Technology, MGM University, Chhatrapati Sambhajinagar (Aurangabad), 431006, MH, India.

Department of Biotechnology, Maulana Azad College of Arts, Science & Commerce, Chhatrapati Sambhajinagar (Aurangabad), 431001, MH, India.

出版信息

Reprod Biol Endocrinol. 2025 Aug 22;23(1):118. doi: 10.1186/s12958-025-01442-8.

Abstract

Emerging evidence highlights the decline of testosterone levels among young males, linked to modern lifestyle shifts rather than aging alone. This exploratory cross-sectional study investigates the interplay between modifiable lifestyle factors and testosterone levels in 50 males aged 18-22 years, focusing on underrepresented variables such as exercise type, carbonated beverage intake, and sunlight exposure. Serum testosterone levels were measured via chemiluminescent immunoassay, and lifestyle data were collected through previously validated questionnaires. Multiple regression analyses revealed hypertrophy training (β = 20.3, p < 0.001), sunlight exposure > 60 min (β = 10.3, p = 0.03), and supplement use (β = 20.5, p < 0.001) as positive predictors of testosterone. Conversely, daily carbonated beverage consumption (β=-10.2, p = 0.01), tobacco use (β=-15.6, p < 0.001), and sleep deprivation (β=-18.2, p < 0.001) were significant negative correlates. Diet type influenced outcomes, with non-vegetarians showing higher testosterone (β = 8.7, p = 0.03) compared to vegetarians. Notably, BMI and chronic diseases were nonsignificant in this young cohort. These findings underscore the multifactorial nature of testosterone regulation, emphasizing holistic lifestyle interventions-such as resistance training, reduced ultra-processed food intake, and sleep optimization-as critical for endocrine health in urbanized youth. The study challenges traditional obesity-centric frameworks, advocating for holistic approaches to mitigate endocrine disruption in emerging adulthood.

摘要

新出现的证据表明,年轻男性的睾酮水平在下降,这与现代生活方式的转变有关,而不仅仅是衰老。这项探索性横断面研究调查了50名年龄在18至22岁之间的男性中可改变的生活方式因素与睾酮水平之间的相互作用,重点关注运动类型、碳酸饮料摄入量和阳光照射等代表性不足的变量。通过化学发光免疫分析法测量血清睾酮水平,并通过先前验证的问卷收集生活方式数据。多元回归分析显示,肥大训练(β = 20.3,p < 0.001)、阳光照射> 60分钟(β = 10.3,p = 0.03)和补充剂使用(β = 20.5,p < 0.001)是睾酮的正向预测因子。相反,每日碳酸饮料消费(β = -10.2,p = 0.01)、吸烟(β = -15.6,p < 0.001)和睡眠不足(β = -18.2,p < 0.001)是显著的负相关因素。饮食类型影响结果,与素食者相比,非素食者的睾酮水平更高(β = 8.7,p = 0.03)。值得注意的是,在这个年轻队列中,BMI和慢性病并不显著。这些发现强调了睾酮调节的多因素性质,强调了诸如阻力训练、减少超加工食品摄入量和优化睡眠等整体生活方式干预对城市化青年内分泌健康的至关重要性。该研究挑战了传统的以肥胖为中心的框架,倡导采用整体方法来减轻成年早期的内分泌干扰。

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