喷他脒的角膜毒性。
Corneal toxicity of propamidine.
作者信息
Johns K J, Head W S, O'Day D M
机构信息
Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN 37232.
出版信息
Arch Ophthalmol. 1988 Jan;106(1):68-9. doi: 10.1001/archopht.1988.01060130074031.
Abstract
Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 0.1% [corrected] propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.
摘要
两名棘阿米巴角膜炎患者在长期使用局部0.1% [校正后] 依西酸丙脒治疗后出现角膜异常。在这两个病例中，停止药物治疗后角膜病变逐渐消退，没有留下永久性后遗症。我们观察到的这些变化可能会与活跃的棘阿米巴感染的变化相混淆。
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