Johns K J, Head W S, O'Day D M
Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, TN 37232.
Arch Ophthalmol. 1988 Jan;106(1):68-9. doi: 10.1001/archopht.1988.01060130074031.
Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 0.1% [corrected] propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.