Department of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Stem Cell Rev Rep. 2021 Aug;17(4):1137-1153. doi: 10.1007/s12015-020-10097-4. Epub 2021 Jan 3.
Cardiac adipose tissue is a metabolically active adipose tissue in close proximity to heart. Recent studies emphasized the benefits of cardiac adipose tissue in heart remodeling, such as reducing infarction size, enhancing neovascularization and regulating immune response, through a series of cellular mechanisms. In the present manuscript, we provide a comprehensive review regarding the role of cardiac adipose tissue in cardiac repair. We focus on different cardiac adipose tissues according to their distinguished anatomical structures. This review summarizes the latest evidence on the relationship between cardiac adipose tissue and cardiac repair. Cardiac adipose tissues (CAT) were systematically reviewed in the current manuscript which focused on the components of CAT, debates about cardiac adipose stem cells and their effect on heart.
心脏脂肪组织是一种紧邻心脏的代谢活跃脂肪组织。最近的研究强调了心脏脂肪组织在心脏重构中的益处，例如通过一系列细胞机制减少梗死面积、增强血管生成和调节免疫反应。在本手稿中，我们提供了关于心脏脂肪组织在心脏修复中的作用的全面综述。我们根据其不同的解剖结构关注不同的心脏脂肪组织。本综述总结了心脏脂肪组织与心脏修复之间关系的最新证据。本文对心脏脂肪组织（CAT）进行了系统综述，重点介绍了 CAT 的组成成分、关于心脏脂肪干细胞的争论及其对心脏的影响。
