早产儿视网膜病变中血小板计数的影响。
Impact of Platelet Count in Retinopathy of Prematurity.
机构信息
Başkent University Faculty of Medicine, Adana Research and Training Center, Department of Ophthalmology, Adana, Turkey.
Başkent University Faculty of Medicine, Adana Research and Training Center, Department of Pediatrics, Division of Neonatology, Adana, Turkey.
出版信息
Turk J Ophthalmol. 2020 Dec 29;50(6):351-355. doi: 10.4274/tjo.galenos.2020.01058.
OBJECTIVES
The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count.
MATERIALS AND METHODS
This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROP including platelet count was evaluated by using logistic regression.
RESULTS
Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factors for developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated with progression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively).
CONCLUSION
Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previously established factors of ventilation need, low BW, and low GA.
目的
本研究旨在探讨早产儿视网膜病变（ROP）的危险因素，包括血小板计数。
材料与方法
本回顾性研究分析了 3 个亚组的 137 名婴儿：无 ROP；轻度 ROP，和需要激光治疗（1 型 ROP）的重度 ROP。对记录进行回顾性审查，并通过逻辑回归评估血小板计数等 ROP 可能危险因素的统计学分析。
结果
出生体重（BW）、胎龄（GA）和出生后第一周的低血小板计数是发生 ROP 的显著危险因素（p=0.038、0.02 和 0.004）。BW、GA、通气和较低的血小板计数与进展为 1 型 ROP 相关（p=0.004；0.027 和 0.021）。
结论
出生后第一周的低血小板计数是 ROP 发展的危险因素，除此之外，还包括先前确定的通气需求、低 BW 和低 GA 等因素。
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