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量子点作为生物传感器用于测定异源物质暴露和毒素中的生化参数

Quantum Dots as Biosensors in the Determination of Biochemical Parameters in Xenobiotic Exposure and Toxins.

作者信息

Ravi Poorvisha, Ganesan Muthupandian

机构信息

Toxicology Division, Regional Forensic Science Laboratory, Forensic Sciences Department, Chennai, 600004, India.

出版信息

Anal Sci. 2021 May 10;37(5):661-671. doi: 10.2116/analsci.20SCR03. Epub 2020 Dec 25.

DOI:10.2116/analsci.20SCR03
PMID:33390416
Abstract

Quantum dots (QDs) have been exploited for a range of scientific applications where the analytes can be expected to have significant photoluminescent properties. Previously, the applications of QDs as nanosensors for the detection of toxics in biospecimens, especially in cases of poisoning, have been discussed. This review focuses on the applications of QDs as biosensors for the detection of phytotoxins, vertebrate and invertebrate toxins, and microbial toxins present in biospecimens. Further, the role of QDs in the measurement of biochemical parameters of patient/victim as an indirect method of poison detection is also highlighted.

摘要

量子点(QDs)已被用于一系列科学应用中,在这些应用中,分析物有望具有显著的光致发光特性。此前,已经讨论了量子点作为纳米传感器在生物样本中检测毒物的应用,特别是在中毒情况下。本综述重点关注量子点作为生物传感器在检测生物样本中存在的植物毒素、脊椎动物和无脊椎动物毒素以及微生物毒素方面的应用。此外,还强调了量子点在测量患者/受害者生化参数作为毒物检测间接方法中的作用。

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Recent developments in diagnostic tools and bioanalytical methods for analysis of snake venom: A critical review.近年来蛇毒分析用诊断工具和生物分析方法的进展:批判性评价。
Anal Chim Acta. 2020 Nov 15;1137:208-224. doi: 10.1016/j.aca.2020.07.054. Epub 2020 Aug 11.
2
Quantum dots as nanosensors for detection of toxics: a literature review.量子点作为纳米传感器用于毒物检测:文献综述。
Anal Methods. 2020 Sep 17;12(35):4254-4275. doi: 10.1039/d0ay01293a.
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Advances in Analysis and Detection of Major Mycotoxins in Foods.食品中主要霉菌毒素的分析与检测进展
Foods. 2020 Apr 20;9(4):518. doi: 10.3390/foods9040518.
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Comparative Study of Time-Resolved Fluorescent Nanobeads, Quantum Dot Nanobeads and Quantum Dots as Labels in Fluorescence Immunochromatography for Detection of Aflatoxin B in Grains.时间分辨荧光纳米珠、量子点纳米珠和量子点在谷物中黄曲霉毒素 B 荧光免疫层析检测中的标记物比较研究。
Biomolecules. 2020 Apr 9;10(4):575. doi: 10.3390/biom10040575.
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Development of quantum dot-based biosensors: principles and applications.基于量子点的生物传感器的发展:原理与应用
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Green synthesis, biomedical and biotechnological applications of carbon and graphene quantum dots. A review.碳量子点和石墨烯量子点的绿色合成、生物医学及生物技术应用。综述
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