Maheshwari Parul, Albert Réka
Department of Physics, The Pennsylvania State University, University Park, PA 16802 USA.
Biology Department, The Pennsylvania State University, University Park, PA 16802 USA.
Appl Netw Sci. 2020;5(1):100. doi: 10.1007/s41109-020-00344-5. Epub 2020 Dec 29.
The first mitigation response to the Covid-19 pandemic was to limit person-to-person interaction as much as possible. This was implemented by the temporary closing of many workplaces and people were required to follow social distancing. Networks are a great way to represent interactions among people and the temporary severing of these interactions. Here, we present a network model of human-human interactions that could be mediators of disease spread. The nodes of this network are individuals and different types of edges denote family cliques, workplace interactions, interactions arising from essential needs, and social interactions. Each individual can be in one of four states: susceptible, infected, immune, and dead. The network and the disease parameters are informed by the existing literature on Covid-19. Using this model, we simulate the spread of an infectious disease in the presence of various mitigation scenarios. For example, lockdown is implemented by deleting edges that denote non-essential interactions. We validate the simulation results with the real data by matching the basic and effective reproduction numbers during different phases of the spread. We also simulate different possibilities of the slow lifting of the lockdown by varying the transmission rate as facilities are slowly opened but people follow prevention measures like wearing masks etc. We make predictions on the probability and intensity of a second wave of infection in each of these scenarios.
对新冠疫情的首个缓解应对措施是尽可能限制人际互动。这通过临时关闭许多工作场所来实现,并且要求人们保持社交距离。网络是表示人与人之间互动以及这些互动的临时切断的一种很好方式。在此,我们提出一种人与人互动的网络模型,这种互动可能是疾病传播的媒介。该网络的节点是个体,不同类型的边表示家庭群体、工作场所互动、因基本需求产生的互动以及社交互动。每个个体可以处于四种状态之一:易感、感染、免疫和死亡。网络和疾病参数参考了关于新冠疫情的现有文献。使用这个模型,我们模拟在各种缓解情景下传染病的传播。例如,通过删除表示非必要互动的边来实施封锁。我们通过匹配传播不同阶段的基本繁殖数和有效繁殖数,用实际数据验证模拟结果。我们还通过在设施缓慢开放但人们遵循戴口罩等预防措施的情况下改变传播率,模拟封锁缓慢解除的不同可能性。我们对每种情景下第二波感染的概率和强度进行预测。