Graduate Program in Physical Education, Universidade Federal de Sergipe, São Cristóvão, Sergipe CEP 49100-000, Brazil.
Group of Studies and Research of Performance, Sport, Health and Paralympic Sports-GEPEPS, Federal University of Sergipe, São Cristóvão, Sergipe CEP 49100-000, Brazil.
Nutrients. 2020 Dec 31;13(1):124. doi: 10.3390/nu13010124.
Diabetes mellitus is one of the most prevalent chronic diseases in the world; one of its main characteristics is chronic hyperglycemia. Pharmacotherapy and other alternatives such as regular exercise are among the therapeutic methods used to control this pathology and participate in glycemic control, as well as the ingestion of plant extracts with antioxidant effects. Among the different plants used for this purpose, curcumin has potential to be used to attenuate the hyperglycemic condition triggered by diabetes mellitus (DM). Some prior studies suggest that this plant has antioxidant and hypoglycemic potential. This review aims to evaluate the antioxidant and hypoglycemic potential of curcumin supplementation in Type 1 DM (T1DM) and Type 2 DM (T2DM). The search considered articles published between 2010 and 2019 in English and Portuguese, and a theoretical survey of relevant information was conducted in the main databases of scientific publications, including the Virtual Health Library and its indexed databases, PubMed, LILACS (Latin American and Caribbean Literature on Health Sciences-Health Information for Latin America and the Caribbean-BIREME/PAHO/WHO), and Scientific Electronic Library Online (SciELO). The associated use of turmeric and physical exercise has demonstrated antioxidant, anti-inflammatory, and hypoglycemic effects, suggesting that these could be used as potential therapeutic methods to improve the quality of life and survival of diabetic patients.
糖尿病是世界上最常见的慢性疾病之一；其主要特征之一是慢性高血糖。药物治疗和其他替代方法，如定期运动，是用于控制这种病理和参与血糖控制的治疗方法之一，以及摄入具有抗氧化作用的植物提取物。在用于此目的的不同植物中，姜黄素具有减轻糖尿病（DM）引起的高血糖状态的潜力。一些先前的研究表明，这种植物具有抗氧化和降血糖的潜力。本综述旨在评估姜黄素补充剂在 1 型糖尿病（T1DM）和 2 型糖尿病（T2DM）中的抗氧化和降血糖潜力。该搜索考虑了 2010 年至 2019 年期间以英语和葡萄牙语发表的文章，并在主要科学出版物数据库中对相关信息进行了理论调查，包括虚拟健康图书馆及其索引数据库、PubMed、LILACS（拉丁美洲和加勒比卫生科学文献-拉丁美洲和加勒比卫生信息-泛美卫生组织/世卫组织）和科学电子图书馆在线（SciELO）。姜黄和体育锻炼的联合使用已证明具有抗氧化、抗炎和降血糖作用，这表明它们可用作改善糖尿病患者生活质量和生存的潜在治疗方法。
