• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于医学应用的Ti-Nb-Zr合金的机械、化学和生物学性能评估。

Assessment of Mechanical, Chemical, and Biological Properties of Ti-Nb-Zr Alloy for Medical Applications.

作者信息

Hoppe Viktoria, Szymczyk-Ziółkowska Patrycja, Rusińska Małgorzata, Dybała Bogdan, Poradowski Dominik, Janeczek Maciej

机构信息

Centre for Advanced Manufacturing Technologies-Fraunhofer Project Center, Department of Laser Technologies, Automation and Production Management, Faculty of Mechanical Engineering, Wrocław University of Science and Technology, 50-371 Wrocław, Poland.

Department of Animal Physiology and Biostructure, Division of Anatomy, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, 50-375 Wrocław, Poland.

出版信息

Materials (Basel). 2020 Dec 30;14(1):126. doi: 10.3390/ma14010126.

DOI:10.3390/ma14010126
PMID:33396757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7796223/
Abstract

The purpose of this work is to obtain comprehensive reference data of the Ti-13Nb-13Zr alloy base material: its microstructure, mechanical, and physicochemical properties. In order to obtain extensive information on the tested materials, a number of examination methods were used, including SEM, XRD, and XPS to determine the phases occurring in the material, while mechanical properties were verified with static tensile, compression, and bending tests. Moreover, the alloy's corrosion resistance in Ringer's solution and the cytotoxicity were investigated using the MTT test. Studies have shown that this alloy has the structure α', α, and β phases, indicating that parts of the β phase transformed to α', which was confirmed by mechanical properties and the shape of fractures. Due to the good mechanical properties (E = 84.1 GPa), high corrosion resistance, as well as the lack of cytotoxicity on MC3T3 and NHDF cells, this alloy meets the requirements for medical implant materials. Ti-13Nb-13Zr alloy can be successfully used in implants, including bone tissue engineering products and dental applications.

摘要

这项工作的目的是获取Ti-13Nb-13Zr合金基材的全面参考数据：其微观结构、力学性能和物理化学性能。为了获得有关测试材料的广泛信息，使用了多种检测方法，包括扫描电子显微镜（SEM）、X射线衍射（XRD）和X射线光电子能谱（XPS）来确定材料中出现的相，同时通过静态拉伸、压缩和弯曲试验验证力学性能。此外，使用MTT试验研究了该合金在林格氏溶液中的耐腐蚀性和细胞毒性。研究表明，该合金具有α'、α和β相结构，表明部分β相转变为α'，这通过力学性能和断口形状得到了证实。由于具有良好的力学性能（弹性模量E = 84.1 GPa）、高耐腐蚀性以及对MC3T3和人正常皮肤成纤维细胞（NHDF）无细胞毒性，该合金符合医用植入材料的要求。Ti-13Nb-13Zr合金可成功用于植入物，包括骨组织工程产品和牙科应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/9b18c0b08f45/materials-14-00126-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/85c776a0461a/materials-14-00126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d2765130fbab/materials-14-00126-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/c266fd44f467/materials-14-00126-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d844f974cf54/materials-14-00126-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/8167bf5b8e32/materials-14-00126-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/6f83876ddf8e/materials-14-00126-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/0ee8eb516ef2/materials-14-00126-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/42fe30900fa9/materials-14-00126-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d16805c98ac3/materials-14-00126-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/5dff5414d349/materials-14-00126-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/914b1c9d57f2/materials-14-00126-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/8eeb549ac6fc/materials-14-00126-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/b8d37b22abab/materials-14-00126-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/9b18c0b08f45/materials-14-00126-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/85c776a0461a/materials-14-00126-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d2765130fbab/materials-14-00126-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/c266fd44f467/materials-14-00126-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d844f974cf54/materials-14-00126-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/8167bf5b8e32/materials-14-00126-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/6f83876ddf8e/materials-14-00126-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/0ee8eb516ef2/materials-14-00126-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/42fe30900fa9/materials-14-00126-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/d16805c98ac3/materials-14-00126-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/5dff5414d349/materials-14-00126-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/914b1c9d57f2/materials-14-00126-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/8eeb549ac6fc/materials-14-00126-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/b8d37b22abab/materials-14-00126-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad0/7796223/9b18c0b08f45/materials-14-00126-g014.jpg

相似文献

1
Assessment of Mechanical, Chemical, and Biological Properties of Ti-Nb-Zr Alloy for Medical Applications.用于医学应用的Ti-Nb-Zr合金的机械、化学和生物学性能评估。
Materials (Basel). 2020 Dec 30;14(1):126. doi: 10.3390/ma14010126.
2
Influence of polyetheretherketone coatings on the Ti-13Nb-13Zr titanium alloy's bio-tribological properties and corrosion resistance.聚醚醚酮涂层对 Ti-13Nb-13Zr 钛合金生物摩擦学性能和耐腐蚀性的影响。
Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:52-61. doi: 10.1016/j.msec.2016.02.043. Epub 2016 Feb 19.
3
Influence of Anodizing Conditions on Biotribological and Micromechanical Properties of Ti-13Zr-13Nb Alloy.阳极氧化条件对Ti-13Zr-13Nb合金生物摩擦学及微观力学性能的影响
Materials (Basel). 2023 Jan 31;16(3):1237. doi: 10.3390/ma16031237.
4
Improved pre-osteoblast response and mechanical compatibility of ultrafine-grained Ti-13Nb-13Zr alloy.改善超细晶 Ti-13Nb-13Zr 合金的成骨前体细胞反应和力学相容性。
Clin Oral Implants Res. 2011 Jul;22(7):735-742. doi: 10.1111/j.1600-0501.2010.02053.x. Epub 2010 Dec 2.
5
New surface-hardened, low-modulus, corrosion-resistant Ti-13Nb-13Zr alloy for total hip arthroplasty.用于全髋关节置换术的新型表面硬化、低模量、耐腐蚀Ti-13Nb-13Zr合金。
Biomed Mater Eng. 1994;4(3):231-43.
6
Microstructure, Micro-Mechanical and Tribocorrosion Behavior of Oxygen Hardened Ti-13Nb-13Zr Alloy.氧强化Ti-13Nb-13Zr合金的微观结构、微观力学及摩擦腐蚀行为
Materials (Basel). 2021 Apr 20;14(8):2088. doi: 10.3390/ma14082088.
7
Nanostructured Ti-13Nb-13Zr alloy for implant application-material scientific, technological, and biological aspects.用于植入应用的纳米结构Ti-13Nb-13Zr合金——材料科学、技术及生物学方面
Front Bioeng Biotechnol. 2023 Aug 24;11:1255947. doi: 10.3389/fbioe.2023.1255947. eCollection 2023.
8
Development of a low elastic modulus and antibacterial Ti-13Nb-13Zr-5Cu titanium alloy by microstructure controlling.通过控制微观结构开发出一种低弹性模量和抗菌的 Ti-13Nb-13Zr-5Cu 钛合金。
Mater Sci Eng C Mater Biol Appl. 2021 Jul;126:112116. doi: 10.1016/j.msec.2021.112116. Epub 2021 Apr 20.
9
Incorporation of Ca ions into anodic oxide coatings on the Ti-13Nb-13Zr alloy by plasma electrolytic oxidation.通过等离子体电解氧化将 Ca 离子掺入 Ti-13Nb-13Zr 合金的阳极氧化涂层中。
Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109957. doi: 10.1016/j.msec.2019.109957. Epub 2019 Jul 16.
10
Production and Characterization of the Third-Generation Oxide Nanotubes on Ti-13Zr-13Nb Alloy.Ti-13Zr-13Nb合金上第三代氧化物纳米管的制备与表征
Materials (Basel). 2022 Mar 21;15(6):2321. doi: 10.3390/ma15062321.

引用本文的文献

1
Assessing Microstructural, Biomechanical, and Biocompatible Properties of TiNb Alloys for Potential Use as Load-Bearing Implants.评估钛铌合金作为承重植入物潜在用途的微观结构、生物力学和生物相容性特性。
J Funct Biomater. 2024 Aug 31;15(9):253. doi: 10.3390/jfb15090253.
2
Dental Implants: Modern Materials and Methods of Their Surface Modification.牙种植体：现代材料及其表面改性方法
Materials (Basel). 2023 Nov 27;16(23):7383. doi: 10.3390/ma16237383.
3
Assessment of Microstructural, Mechanical and Electrochemical Properties of Ti-42Nb Alloy Manufactured by Electron Beam Melting.

本文引用的文献

1
Review of titanium surface modification techniques and coatings for antibacterial applications.钛表面改性技术及抗菌涂层的研究进展。
Acta Biomater. 2019 Jan 1;83:37-54. doi: 10.1016/j.actbio.2018.10.036. Epub 2018 Oct 26.
2
Improvement to the Corrosion Resistance of Ti-Based Implants Using Hydrothermally Synthesized Nanostructured Anatase Coatings.利用水热合成纳米结构锐钛矿涂层提高钛基植入物的耐腐蚀性
Materials (Basel). 2014 Jan 2;7(1):180-194. doi: 10.3390/ma7010180.
3
Customized a Ti6Al4V Bone Plate for Complex Pelvic Fracture by Selective Laser Melting.
电子束熔炼制备的Ti-42Nb合金的微观结构、力学性能及电化学性能评估
Materials (Basel). 2023 Jul 4;16(13):4821. doi: 10.3390/ma16134821.
4
Electrochemical and biological characterization of Ti-Nb-Zr-Si alloy for orthopedic applications.用于骨科应用的 Ti-Nb-Zr-Si 合金的电化学和生物学特性。
Sci Rep. 2023 Feb 9;13(1):2312. doi: 10.1038/s41598-023-29553-5.
5
Antibiotic-free antimicrobial poly (methyl methacrylate) bone cements: A state-of-the-art review.无抗生素抗菌聚甲基丙烯酸甲酯骨水泥：最新综述
World J Orthop. 2022 Apr 18;13(4):339-353. doi: 10.5312/wjo.v13.i4.339.
6
Addressing the Needs of the Rapidly Aging Society through the Development of Multifunctional Bioactive Coatings for Orthopedic Applications.通过开发用于骨科应用的多功能生物活性涂层来满足快速老龄化社会的需求。
Int J Mol Sci. 2022 Mar 3;23(5):2786. doi: 10.3390/ijms23052786.
7
A Novel Multiaxial Strain-Based Criterion Considering Additional Cyclic Hardening.一种考虑额外循环硬化的基于多轴应变的新型准则。
Materials (Basel). 2021 May 13;14(10):2542. doi: 10.3390/ma14102542.
通过选择性激光熔化定制用于复杂骨盆骨折的Ti6Al4V骨板。
Materials (Basel). 2017 Jan 4;10(1):35. doi: 10.3390/ma10010035.
4
Biomedical titanium alloys with Young's moduli close to that of cortical bone.具有接近皮质骨杨氏模量的生物医用钛合金。
Regen Biomater. 2016 Sep;3(3):173-85. doi: 10.1093/rb/rbw016. Epub 2016 Mar 8.
5
Surgical planning, manufacturing and implantation of an individualized cervical fusion titanium cage using patient-specific data.利用患者特异性数据进行个性化颈椎融合钛笼的手术规划、制造和植入。
Eur Spine J. 2016 Jul;25(7):2239-46. doi: 10.1007/s00586-016-4473-9. Epub 2016 Mar 1.
6
Implantation of customized 3-D printed titanium prosthesis in limb salvage surgery: a case series and review of the literature.定制3D打印钛合金假体在保肢手术中的植入：病例系列及文献综述
World J Surg Oncol. 2015 Nov 4;13:308. doi: 10.1186/s12957-015-0723-2.
7
Tribological and corrosion behaviors of warm-and hot-rolled Ti-13Nb-13Zr alloys in simulated body fluid conditions.温热轧和热轧Ti-13Nb-13Zr合金在模拟体液条件下的摩擦学与腐蚀行为
Int J Nanomedicine. 2015 Oct 1;10 Suppl 1(Suppl 1):207-12. doi: 10.2147/IJN.S79996. eCollection 2015.
8
Implant-abutment connections: influence of the design on the microgap and their fatigue and fracture behavior of dental implants.种植体-基台连接：设计对种植体微间隙及其疲劳和断裂行为的影响。
J Mater Sci Mater Med. 2014 Jul;25(7):1825-30. doi: 10.1007/s10856-014-5211-7. Epub 2014 Apr 10.
9
Are new TiNbZr alloys potential substitutes of the Ti6Al4V alloy for dental applications? An electrochemical corrosion study.新型 TiNbZr 合金是否有可能成为牙科应用中 Ti6Al4V 合金的替代品？电化学腐蚀研究。
Biomed Mater. 2013 Dec;8(6):065005. doi: 10.1088/1748-6041/8/6/065005. Epub 2013 Nov 26.
10
Cytocompatibility of pure metals and experimental binary titanium alloys for implant materials.用于植入材料的纯金属及实验性二元钛合金的细胞相容性
J Dent. 2013 Dec;41(12):1251-8. doi: 10.1016/j.jdent.2013.09.003. Epub 2013 Sep 20.