Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
Department of Organic Technology, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
Int J Mol Sci. 2020 Dec 30;22(1):312. doi: 10.3390/ijms22010312.
The properties of materials at the nanoscale open up new methodologies for engineering prospective materials usable in high-end applications. The preparation of composite materials with a high content of an active component on their surface is one of the current challenges of materials engineering. This concept significantly increases the efficiency of heterogeneous processes moderated by the active component, typically in biological applications, catalysis, or drug delivery. Here we introduce a general approach, based on laser-induced optomechanical processing of silver colloids, for the preparation of polymer surfaces highly enriched with silver nanoparticles (AgNPs). As a result, the AgNPs are firmly immobilized in a thin surface layer without the use of any other chemical mediators. We have shown that our approach is applicable to a broad spectrum of polymer foils, regardless of whether they absorb laser light or not. However, if the laser radiation is absorbed, it is possible to transform smooth surface morphology of the polymer into a roughened one with a higher specific surface area. Analyses of the release of silver from the polymer surface together with antibacterial tests suggested that these materials could be suitable candidates in the fight against nosocomial infections and could inhibit the formation of biofilms with a long-term effect.
纳米尺度下材料的特性为工程学带来了新的方法，使具有前瞻性的材料可应用于高端领域。制备表面高浓度活性成分的复合材料是材料工程当前面临的挑战之一。这一概念极大地提高了活性成分调节的多相过程的效率，在生物应用、催化或药物输送中尤为如此。在此，我们提出了一种基于激光诱导胶体银光机械处理的通用方法，用于制备高度富集银纳米粒子（AgNPs）的聚合物表面。结果是，AgNPs 被牢固地固定在薄的表面层中，而无需使用任何其他化学介质。我们已经证明，我们的方法适用于广泛的聚合物箔，无论它们是否吸收激光。然而，如果激光辐射被吸收，则有可能将聚合物的光滑表面形貌转变为具有更高比表面积的粗糙形貌。对聚合物表面释放银的分析以及抗菌测试表明，这些材料可能是对抗医院感染的合适候选物，并能抑制生物膜的形成，具有长期效果。
