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国家卫生安全准备指数作为新冠病毒疾病超额死亡率预测指标的有效性

Validity of the National Health Security Preparedness Index as a Predictor of Excess COVID-19 Mortality.

作者信息

Keim Mark E, Lovallo Alex P

机构信息

DisasterDoc LLC, Atlanta, GeorgiaUSA.

Beth Israel Deaconess Medical Center Disaster Medicine Fellowship, Harvard University, Boston, MassachusettsUSA.

出版信息

Prehosp Disaster Med. 2021 Apr;36(2):141-144. doi: 10.1017/S1049023X20001521. Epub 2021 Jan 5.

Abstract

OBJECTIVE

This study compared 2019 values for the National Health Security Preparedness Index (NHSPI) with 2020 rates of coronavirus disease 2019 (COVID-19)-related mortality as reported by the 50 US states and Puerto Rico during the first six months of the US pandemic (March 1 - August 31, 2020).

METHODS

Data regarding provisional death counts and estimates of excess deaths for COVID-19 according to state and territory were downloaded from the Centers for Disease Control and Prevention (CDC) National Center for Health Statistics website. Reporting included the six-month-long period of March 1 - August 31, 2020. Excess mortality rates were calculated as the number of excess deaths per 100,000 persons in each state population using 2019 US Census Bureau data. Mean values for state and territorial NHSPI domain indices were compared to state and territorial rates of COVID-19-related excess mortality using multiple linear regression, including analysis of variance. Correlations between the 51 state and territorial NHSPI values and corresponding COVID-19 excess mortality rates were calculated using Pearson's correlation coefficient.

RESULTS

These calculations revealed a high degree of variance (adjusted r square = 0.02 and 0.25) and poor correlation (P = .16 and .08) among values for the overall NHSPI as compared to low and high estimates of excess COVID-19 mortality rates for 50 US states and Puerto Rico.There was also a high degree of variance (adjusted r square = 0.001 and 0.03) and poor correlation (P values ranging from .09 to .94) for values for the six individual domains of the NHSPI as compared to low and high estimates of excess COVID-19 mortality rates for 50 US states and Puerto Rico.

CONCLUSION

The NHSPI does not appear to be a valid predictor of excess COVID-19 mortality rates for 50 US states and Puerto Rico during the first six months of the pandemic.

摘要

目的

本研究将2019年美国国家安全防备指数(NHSPI)的值与美国50个州和波多黎各在2020年美国疫情前六个月(2020年3月1日至8月31日)报告的2019冠状病毒病(COVID-19)相关死亡率进行了比较。

方法

根据州和地区,从疾病控制与预防中心(CDC)国家卫生统计中心网站下载了关于COVID-19临时死亡人数和超额死亡估计数的数据。报告涵盖2020年3月1日至8月31日这六个月期间。使用2019年美国人口普查局数据,将超额死亡率计算为每个州人口中每10万人的超额死亡人数。使用多元线性回归(包括方差分析),将州和地区NHSPI领域指数的平均值与COVID-19相关超额死亡率进行比较。使用Pearson相关系数计算51个州和地区NHSPI值与相应COVID-19超额死亡率之间的相关性。

结果

这些计算表明,与美国50个州和波多黎各COVID-19超额死亡率的低估值和高估值相比,总体NHSPI值之间存在高度差异(调整后r平方 = 0.02和0.25)且相关性较差(P = 0.16和0.08)。与美国50个州和波多黎各COVID-19超额死亡率的低估值和高估值相比,NHSPI六个单独领域的值也存在高度差异(调整后r平方 = 0.001和0.03)且相关性较差(P值范围从0.09到0.94)。

结论

在疫情的前六个月,NHSPI似乎不是美国50个州和波多黎各COVID-19超额死亡率的有效预测指标。

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