紫外线引发掺杂氧化锌纳米颗粒的电纺壳聚糖/聚环氧乙烷纳米纤维的交联：抗菌纳米纤维水凝胶的研制
UV-initiated crosslinking of electrospun chitosan/poly(ethylene oxide) nanofibers doped with ZnO-nanoparticles: development of antibacterial nanofibrous hydrogel.
作者信息
Estrada-Villegas G M, Del Río-De Vicente J I, Argueta-Figueroa L, González-Pérez G
机构信息
CONACyT - Centro de Investigación en Química Aplicada, Av. Alianza Sur 204 Parque de Innovación e Investigación Tecnológica, Apodaca, Nuevo León, 66629 Mexico.
CONACyT - Facultad de Odontología, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca, 68120 Mexico.
出版信息
MRS Commun. 2020;10(4):642-651. doi: 10.1557/mrc.2020.74. Epub 2020 Dec 24.
UNLABELLED
UV-initiated crosslinking of electrospun poly(ethylene) oxide (PEO)/chitosan (CS) nanofibers doped with zinc oxide nanoparticles (ZnO-NPs) was performed using pentaerythritol triaclyrate (PETA) as the photoinitiator and crosslinker agent. The influence of the addition of PETA to the PEO/CS diameter and crosslinking of nanofibers was evaluated. The effect of irradiation time on the morphology and swelling properties of the crosslinked nanofibers were investigated. For ZnO-NPs, the minimum inhibitory concentrations were found at 1 mg/mL, and the minimum bactericidal concentrations at 2 mg/mL for all the strains tested. The nanofibrous hydrogel antibacterial effect was tested. This material enters the realm of fibrous hydrogels which have potential use in several applications as in the biomedical area.
SUPPLEMENTARY MATERIAL
The supplementary material for this article can be found at 10.1557/mrc.2020.74.
未标注
以季戊四醇三丙烯酸酯（PETA）作为光引发剂和交联剂，对掺杂氧化锌纳米颗粒（ZnO-NPs）的静电纺聚环氧乙烷（PEO）/壳聚糖（CS）纳米纤维进行紫外光引发交联。评估了添加PETA对PEO/CS纳米纤维直径和交联的影响。研究了辐照时间对交联纳米纤维形态和溶胀性能的影响。对于ZnO-NPs，在所测试的所有菌株中，最低抑菌浓度为1 mg/mL，最低杀菌浓度为2 mg/mL。测试了纳米纤维水凝胶的抗菌效果。这种材料进入了纤维水凝胶领域，在生物医学等多个应用领域具有潜在用途。
补充材料
本文的补充材料可在10.1557/mrc.2020.74获取。
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