Moore Phoebe S, Mokrova Irina, Frazier Jean A, Joseph Robert M, Santos Hudson P, Dvir Yael, Hooper Stephen R, O'Shea T Michael, Douglass Laurie M, Kuban Karl C K
Department of Psychiatry and the Eunice Kennedy Shriver Center, University of Massachusetts Medical School.
Duke University School of Medicine.
J Pediatr Psychol. 2021 Apr 16;46(4):422-432. doi: 10.1093/jpepsy/jsaa118.
Objective Anxiety and depression rates are known to be elevated in prematurely-born children and adolescents. This prospective study examines demographic, academic, and physical health correlates of anxiety and depression symptoms in a sample of 10-year-old children who were born extremely preterm. Methods Participants were 889 (51.2% male; 62.3% White) children who were born <28 weeks gestation. Child and family demographic data were collected at birth. When the children were 10, parents (n = 871) and teachers (n = 640) rated the level of anxiety and depression in children through the Child Symptom Inventory-4. Child academic functioning was assessed via the Wechsler Individual Achievement Test-III. Parents completed questionnaires about child academic functioning and physical health issues. Data analyses were conducted with multivariate linear modeling. Results Level of prematurity was significantly related to both parent and teacher reports of anxiety. Public health insurance and individualized education program (IEP) status were associated with both parent and teacher reports of depression. Hispanic ethnicity, public insurance, IEP status, and asthma were significantly associated with both parent-reported anxiety and depression. Gross motor impairment was associated with parent-reported anxiety and teacher-reported depression. Child obesity was associated with teacher reports of anxiety, while male sex was significantly related to teacher reports of depression. Conclusion This pattern of findings may suggest hypotheses for future research on models of the development and persistence of anxiety and depression within this particularly vulnerable group of children.
早产儿童和青少年的焦虑和抑郁发生率较高。这项前瞻性研究调查了10岁极早产儿样本中焦虑和抑郁症状与人口统计学、学业及身体健康状况之间的关联。
研究对象为889名(51.2%为男性;62.3%为白人)孕龄小于28周出生的儿童。在出生时收集儿童及家庭的人口统计学数据。当儿童10岁时,父母(n = 871)和教师(n = 640)通过儿童症状量表-4对儿童的焦虑和抑郁程度进行评分。通过韦氏个别成就测验-III评估儿童的学业表现。父母完成有关儿童学业表现和身体健康问题的问卷。采用多元线性模型进行数据分析。
早产程度与父母和教师报告的焦虑均显著相关。公共医疗保险和个别化教育计划(IEP)状态与父母和教师报告的抑郁均相关。西班牙裔种族、公共保险、IEP状态和哮喘与父母报告的焦虑和抑郁均显著相关。大运动功能障碍与父母报告的焦虑和教师报告的抑郁相关。儿童肥胖与教师报告的焦虑相关,而男性性别与教师报告的抑郁显著相关。
这一研究结果模式可能为未来针对这一特别脆弱儿童群体中焦虑和抑郁的发展及持续模式的研究提出假设。