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Significance of single-cell and spatial transcriptomes in cell biology and toxicology.

作者信息

Wu Duojiao, Liu Xiaozhuan, Zhang Jiaqiang, Li Li, Wang Xiangdong

机构信息

Zhongshan Hospital Institute for Clinical Science, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Zhongshan Hospital, Fudan University, Shanghai, China; Jinshan Hospital Centre for Tumor Diagnosis and Therapy, Jinshan Hospital, Fudan University, Shanghai, China.

Clinical Center for Single Cell Biomedicine, People's Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Cell Biol Toxicol. 2021 Feb;37(1):1-5. doi: 10.1007/s10565-020-09576-8. Epub 2021 Jan 4.

DOI:10.1007/s10565-020-09576-8
PMID:33398619
Abstract
摘要

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Annu Rev Genomics Hum Genet. 2020 Aug 31;21:163-181. doi: 10.1146/annurev-genom-120219-083220. Epub 2020 Apr 27.
2
Single-cell biomedicine: roles of single-cell nuclear elements.单细胞生物医学：单细胞核元件的作用
Cell Biol Toxicol. 2020 Feb;36(1):1-3. doi: 10.1007/s10565-020-09515-7. Epub 2020 Feb 1.
3
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
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Signal Transduct Target Ther. 2022 Apr 1;7(1):111. doi: 10.1038/s41392-022-00960-w.
4
Clinical challenges of tissue preparation for spatial transcriptome.空间转录组学组织准备的临床挑战。
Clin Transl Med. 2022 Jan;12(1):e669. doi: 10.1002/ctm2.669.
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Can single cell RNA sequencing reshape the clinical biochemistry of hematology: New clusters of circulating blood cells.单细胞 RNA 测序能否重塑血液学生化临床检验学：循环血细胞的新簇。
Clin Transl Med. 2021 Dec;11(12):e671. doi: 10.1002/ctm2.671.
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IEEE Trans Biomed Eng. 2022 Jan;69(1):412-421. doi: 10.1109/TBME.2021.3096126. Epub 2021 Dec 23.
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