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基因组证据表明,尽管在出发前进行了检测,但仍有 SARS-CoV-2 在飞行途中传播。

Genomic Evidence of In-Flight Transmission of SARS-CoV-2 Despite Predeparture Testing.

出版信息

Emerg Infect Dis. 2021 Mar;27(3):687-693. doi: 10.3201/eid2703.204714. Epub 2021 Jan 5.

DOI:10.3201/eid2703.204714
PMID:33400642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7920679/
Abstract

Since the first wave of coronavirus disease in March 2020, citizens and permanent residents returning to New Zealand have been required to undergo managed isolation and quarantine (MIQ) for 14 days and mandatory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of October 20, 2020, of 62,698 arrivals, testing of persons in MIQ had identified 215 cases of SARS-CoV-2 infection. Among 86 passengers on a flight from Dubai, United Arab Emirates, that arrived in New Zealand on September 29, test results were positive for 7 persons in MIQ. These passengers originated from 5 different countries before a layover in Dubai; 5 had negative predeparture SARS-CoV-2 test results. To assess possible points of infection, we analyzed information about their journeys, disease progression, and virus genomic data. All 7 SARS-CoV-2 genomes were genetically identical, except for a single mutation in 1 sample. Despite predeparture testing, multiple instances of in-flight SARS-CoV-2 transmission are likely.

摘要

自 2020 年 3 月第一波冠状病毒病以来,返回新西兰的公民和永久居民被要求进行 14 天的管理隔离和检疫(MIQ)和对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)进行强制性检测。截至 2020 年 10 月 20 日,在 62698 名抵达者中,MIQ 中的人员检测已确定 215 例 SARS-CoV-2 感染病例。9 月 29 日,从阿拉伯联合酋长国迪拜抵达新西兰的一架航班上有 86 名乘客,MIQ 中有 7 人的检测结果呈阳性。这些乘客在迪拜停留前来自 5 个不同的国家;5 人在出发前 SARS-CoV-2 检测结果为阴性。为了评估可能的感染点,我们分析了他们旅行、疾病进展和病毒基因组数据的信息。除了 1 个样本中的单个突变外,所有 7 个 SARS-CoV-2 基因组都是完全相同的。尽管进行了出发前的检测,但在飞行过程中很可能发生多次 SARS-CoV-2 传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/e481d8b2b32a/20-4714-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/dc7712fd4ab6/20-4714-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/451bdfe3f27d/20-4714-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/7c333ec66cf4/20-4714-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/0fec747eaf9e/20-4714-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/e481d8b2b32a/20-4714-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/dc7712fd4ab6/20-4714-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/451bdfe3f27d/20-4714-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/7c333ec66cf4/20-4714-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/0fec747eaf9e/20-4714-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc0e/7920679/e481d8b2b32a/20-4714-F5.jpg

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