Emerg Infect Dis. 2021 May;27(5):1274-1278. doi: 10.3201/eid2705.210514. Epub 2021 Mar 18.
The strategy in New Zealand (Aotearoa) to eliminate coronavirus disease requires that international arrivals undergo managed isolation and quarantine and mandatory testing for severe acute respiratory syndrome coronavirus 2. Combining genomic and epidemiologic data, we investigated the origin of an acute case of coronavirus disease identified in the community after the patient had spent 14 days in managed isolation and quarantine and had 2 negative test results. By combining genomic sequence analysis and epidemiologic investigations, we identified a multibranched chain of transmission of this virus, including on international and domestic flights, as well as a probable case of aerosol transmission without direct person-to-person contact. These findings show the power of integrating genomic and epidemiologic data to inform outbreak investigations.
新西兰(Aotearoa)消除冠状病毒病的策略要求国际入境者接受管理式隔离和检疫,并对严重急性呼吸系统综合症冠状病毒 2 进行强制性检测。我们结合基因组和流行病学数据,调查了在患者接受管理式隔离和检疫 14 天后,在社区中发现的急性冠状病毒病病例的起源,该患者有 2 次阴性检测结果。通过结合基因组序列分析和流行病学调查,我们确定了该病毒的多分支传播链,包括国际和国内航班,以及可能的无直接人际接触的气溶胶传播病例。这些发现表明了整合基因组和流行病学数据以提供暴发调查信息的力量。