School of Computing and Information Systems, The University of Melbourne, Melbourne, Australia.
School of Mathematical Sciences, The University of Adelaide, Adelaide, Australia.
J R Soc Interface. 2021 Jan;18(174):20200657. doi: 10.1098/rsif.2020.0657. Epub 2021 Jan 6.
COVID-19 is highly transmissible and containing outbreaks requires a rapid and effective response. Because infection may be spread by people who are pre-symptomatic or asymptomatic, substantial undetected transmission is likely to occur before clinical cases are diagnosed. Thus, when outbreaks occur there is a need to anticipate which populations and locations are at heightened risk of exposure. In this work, we evaluate the utility of aggregate human mobility data for estimating the geographical distribution of transmission risk. We present a simple procedure for producing spatial transmission risk assessments from near-real-time population mobility data. We validate our estimates against three well-documented COVID-19 outbreaks in Australia. Two of these were well-defined transmission clusters and one was a community transmission scenario. Our results indicate that mobility data can be a good predictor of geographical patterns of exposure risk from transmission centres, particularly in outbreaks involving workplaces or other environments associated with habitual travel patterns. For community transmission scenarios, our results demonstrate that mobility data add the most value to risk predictions when case counts are low and spatially clustered. Our method could assist health systems in the allocation of testing resources, and potentially guide the implementation of geographically targeted restrictions on movement and social interaction.
COVID-19 具有高度传染性,控制疫情爆发需要快速有效的应对措施。由于感染可能发生在有症状或无症状的人身上,因此在临床确诊病例出现之前,很可能已经发生了大量未被发现的传播。因此,当疫情爆发时,需要预测哪些人群和地点面临更高的暴露风险。在这项工作中,我们评估了综合人类流动性数据在估计传播风险的地理分布方面的效用。我们提出了一种从近实时人口流动数据生成空间传播风险评估的简单方法。我们通过澳大利亚的三次有充分记录的 COVID-19 疫情来验证我们的估计。其中两个是明确的传播集群,一个是社区传播情况。我们的结果表明,移动性数据可以很好地预测来自传播中心的暴露风险的地理模式,特别是在涉及与习惯性旅行模式相关的工作场所或其他环境的疫情爆发中。对于社区传播情况,我们的结果表明,当病例数量较少且呈空间聚集时,移动性数据对风险预测的附加值最大。我们的方法可以帮助卫生系统分配检测资源,并有可能指导对移动和社会互动实施有针对性的地理限制。