Gregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Vienna BioCenter, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
Plant Commun. 2019 Dec 14;1(1):100015. doi: 10.1016/j.xplc.2019.100015. eCollection 2020 Jan 13.
The eukaryotic nucleosome prevents access to the genome. Convergently evolving histone isoforms, also called histone variants, form diverse families that are enriched over distinct features of plant genomes. Among the diverse families of plant histone variants, H2A.Z exclusively marks genes. Here we review recent research progress on the genome-wide distribution patterns and deposition of H2A.Z in plants as well as its association with histone modifications and roles in plant chromatin regulation. We also discuss some hypotheses that explain the different findings about the roles of H2A.Z in plants.
真核生物核小体阻止了基因组的可接近性。趋同进化的组蛋白同工型，也称为组蛋白变体，形成了多样化的家族，这些家族在植物基因组的不同特征上富集。在植物组蛋白变体的多样化家族中，H2A.Z 专门标记基因。本文综述了 H2A.Z 在植物基因组中的全基因组分布模式和沉积及其与组蛋白修饰的关联，以及在植物染色质调控中的作用的最新研究进展。我们还讨论了一些假设，这些假设解释了 H2A.Z 在植物中的作用的不同发现。
